CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11609
Family Name Inhibitor of nuclear factor kappa-B kinase subunit beta and Inhibitor of nuclear factor kappa-B kinase subunit alpha inhibitor N-(2-hydroxyethyl)-4-(2-propan-2-yl-1H-pyrrolo[2,3-b]pyridin-4-yl)benzenesulfonamide family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00409480 Functional Category Bioactive
Superfamily Serine/threonine-protein kinase B-raf Inhibitor GSK2118436 Superfamily
Class Class 1174

Cousin Family NamesSeedsMembers
C-X-C chemokine receptor type 4 Ligand AMD-070 Family 12 800
D(4) dopamine receptor Ligand L-745,870 Family 30 205
Interleukin-1 receptor type 1 and Mitogen-activated protein ki... 7 151
Beta-secretase 1 Inhibitor 6-[2-(1h-indol-6-yl)ethyl]pyridin-2... 10 43
Arachidonate 5-lipoxygenase Inhibitor 2,4,5-triarylimidazole A... 3 16
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Hepatocyte growth factor receptor Ligand 3-(phenylsulfonyl)-1h... 17 59
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family 6 13
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Coagulation factor X and Trypsin-1 inhibitor 2-(5-carbamimidoy... 5 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Mitogen-activated protein kinase 14 inhibitor 6-[5-(2,4-difluo... 9 3
Cyclin-dependent kinase 1 inhibitor 4-[[4-(3H-benzimidazol-5-y... 1 0
Aurora kinase B and Vascular endothelial growth factor recepto... 1 2
High affinity nerve growth factor receptor ligand N-[3-amino-5... 4 10
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2152398 family 16 1
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 3 4
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 4 5
Cathepsin K and Cathepsin S inhibitor SureCN4138353 family 3 0
Prostaglandin G/H synthase 2 inhibitor 4-N,4-N-diethyl-2-(4-me... 5 1
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 1 0
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 2 3
5-hydroxytryptamine receptor 2B ligand SureCN1299053 family 1 1
LIM domain kinase 2 inhibitor (2S)-N-cyano-N'-[3-(2-hydroxyeth... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27759 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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