CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11615
Family Name Bombesin receptor subtype-3 and Nuclear receptor subfamily 1 group I member 2 ligand 6-(4-tert-butylphenyl)sulfonyl-7-pyridin-3-yl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00393132 Functional Category Bioactive
Superfamily Bombesin receptor subtype-3 and Nuclear receptor subfamily 1 group I member 2 Binder Superfamily
Class Class 122

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Vascular endothe... 6 34
Neuropeptide Y receptor type 5 Ligand CGP71683A Family 5 74
Transient receptor potential cation channel subfamily V member... 15 457
Mitogen-activated protein kinase 14 and Tyrosine-protein kinas... 3 9
Corticosteroid 11-beta-dehydrogenase isozyme 1 Inhibitor 2-(4-... 8 25
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Potassium voltage-gated channel subfamily H member 2 Ligand AZ... 21 42
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family 6 13
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 27
Carbonic anhydrase 9 and Carbonic anhydrase 2 inhibitor AGN-PC... 1 0
Coagulation factor X and Trypsin-1 inhibitor SureCN3836037 family 5 4
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (2R)-... 5 10
Neuropeptide Y receptor type 5 ligand SureCN8898853 family 2 3
Tyrosine-protein kinase JAK2 inhibitor N-tert-butyl-3-[2-[3-fl... 4 14
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 11
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 8
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 15 3
Aurora kinase B and Vascular endothelial growth factor recepto... 1 2
High affinity nerve growth factor receptor ligand N-[3-amino-5... 4 10
Serine/threonine-protein kinase SMG1 and Serine/threonine-prot... 10 0
Serine/threonine-protein kinase SMG1 and Cyclin-dependent kina... 3 1
Bombesin receptor subtype-3 ligand 2-[3-[6-(4-tert-butylphenyl... 7 1
Bombesin receptor subtype-3 and Nuclear receptor subfamily 1 g... 12 11
Bombesin receptor subtype-3 ligand 6-(4-tert-butylphenyl)sulfo... 3 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 3
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 3 1
Cyclin-dependent kinase 2 inhibitor Imidazo[1,2-b]pyridazine d... 2 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name


Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27254 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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