CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11618
Family Name Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)phenyl]methyl]-N-pyridin-3-ylpiperazine-1-carboxamide family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00151278 Functional Category Bioactive
Superfamily Fatty-acid amide hydrolase 1 and Cytochrome P450 3A4 Binder Superfamily
Class Class 6

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase B-raf inhibitor diaryl urea an... 12 93
Epidermal growth factor receptor and Receptor tyrosine-protein... 8 31
Receptor tyrosine-protein kinase erbB-2 Inhibitor TAK-285 Family 16 124
Angiopoietin-1 receptor and Tyrosine-protein kinase Lck Inhibi... 3 64
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
Potassium voltage-gated channel subfamily H member 2 Ligand Be... 22 56
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 39 10
Reverse transcriptase/RNaseH inhibitor 1-[2-(6-chloro-3-ethoxy... 7 5
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Fatty-acid amide hydrolase 1 and Cytochrome P450 2D6 inhibitor... 2 0
Insulin-like growth factor 1 receptor and Potassium voltage-ga... 2 2
Translocator protein inhibitor 2-fluoro-N-[(2-methoxyphenyl)me... 8 27
Cystic fibrosis transmembrane conductance regulator inhibitor ... 2 2
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 6 2
Cholesteryl ester transfer protein inhibitor 1-[(1S)-1-(5-chlo... 11 8
Nitric oxide synthase, inducible inhibitor 2-[1-(2-imidazol-1-... 4 3
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 4 2
Fatty-acid amide hydrolase 1 inhibitor N-(2,1,3-benzothiadiazo... 1 1
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 1 0
Fatty-acid amide hydrolase 1 inhibitor 4-[[3-(4-chlorophenoxy)... 1 1
P2Y purinoceptor 1 inhibitor 1-(4-tert-butylphenyl)-3-[2-(2-pr... 4 14
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand pheny... 1 0
Vascular endothelial growth factor receptor 2 ligand N-(4-chlo... 4 4
Reverse transcriptase/RNaseH inhibitor 1-(5-chloropyridin-2-yl... 3 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 1
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 4 3
Macrophage colony-stimulating factor 1 receptor ligand AGN-PC-... 1 3
Acyl-CoA desaturase 1 inhibitor AGN-PC-077KJ2 family 1 0
Bifunctional epoxide hydrolase 2 and Voltage-dependent L-type ... 2 1
Acyl-CoA:cholesterol acyltransferase inhibitor 3-(2-chloro-6-m... 4 6
Coagulation factor X and Cationic trypsin inhibitor SureCN6578... 4 11
Histidine-rich protein PFHRP-II inhibitor AGN-PC-075SYG family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00410669 CHEMBL2207343 Bioactive 4-[[3-(4-chlorophenoxy)phenyl]methyl]-N-isoquinolin-4-ylpiperazine-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

45918 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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