CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11630
Family Name Fatty-acid amide hydrolase 1 inhibitor [3-(3-carbamoylpyrrol-1-yl)phenyl] N-[2-[2-(4-fluorophenoxy)ethoxy]ethyl]carbamate family
No. of Seeds 4 No. of Other Members 6
Family Centroid CFAMM00410701 Functional Category Bioactive with Natural Product
Superfamily Reverse transcriptase/RNaseH and Prelamin-A/C Binder Superfamily
Class Class 2593

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
Sodium channel protein type 5 subunit alpha Ligand Dibucaine F... 2 136
Mast/stem cell growth factor receptor Kit and Vascular endothe... 1 4
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
von Willebrand factor Inhibitor Auryntricarboxylic Acid (ata) ... 12 81
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 13 22
5-hydroxytryptamine receptor 2A Ligand [2-(6-methoxy-indol-1-y... 2 10
Cannabinoid receptor 2 Ligand JWH-202 Family 9 172
DNA-dependent protein kinase catalytic subunit Inhibitor 8-(1h... 3 85
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 14 214
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 31
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Vasopressin V1a receptor and Vasopressin V2 receptor ligand (3... 4 41
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 1 18
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand SureC... 8 32
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 8 21
Vascular endothelial growth factor receptor 2 and Aurora kinas... 3 3
Renin inhibitor AGN-PC-09M9MJ family 2 23
Growth hormone secretagogue receptor type 1 ligand 2-amino-N-[... 3 3
Poly [ADP-ribose] polymerase 1 inhibitor SureCN5002485 family 2 11
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 16
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 15
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 19
MAP kinase-activated protein kinase 2 inhibitor CHEMBL1801290 ... 3 0
Renin inhibitor [2-(3-fluoro-2,6-dimethylphenoxy)-1-phenylpyrr... 5 12
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 5 2
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 19 10
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 2
Translocator protein inhibitor (4S)-N,N-diethyl-9-(2-fluoranyl... 9 10
Histamine H3 receptor ligand 2-[4-(1-methylpyrrole-2-carbonyl)... 3 4
Disintegrin and metalloproteinase domain-containing protein 17... 16 2
Sonic hedgehog protein inhibitor 3-methoxy-1-methyl-4-oxo-5-ph... 5 3
Seprase and Prolyl endopeptidase inhibitor N-[2-[(2S)-2-cyanop... 1 3
Glutamate receptor ionotropic, NMDA 2B ligand SureCN5532501 fa... 1 0
Platelet-activating factor receptor ligand N,N-dimethyl-6-phen... 12 18
Histone deacetylase 3 and Histone deacetylase 9 inhibitor AGN-... 4 20
Cathepsin K inhibitor N-[(2S)-4-methyl-1-[2-[4-(2-methylpropox... 4 0
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 6 8
Vasopressin V2 receptor and Vasopressin V1a receptor ligand Su... 2 2
Interstitial collagenase and Matrilysin inhibitor (3S,6R,7S)-N... 2 4
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 1 0
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 1
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-(3-me... 2 10
Substance-P receptor ligand AGN-PC-0D60L0 family 2 7
Melatonin receptor type 1A and Melatonin receptor type 1B liga... 2 3
Mitogen-activated protein kinase 14 inhibitor SureCN4508019 fa... 1 0
Vascular endothelial growth factor receptor 2 ligand (4Z)-4-[(... 3 0
Platelet-derived growth factor receptor beta and Vascular endo... 1 3
Pol polyprotein inhibitor Phenprocoumon IndolEtCONH deriv. family 2 0
NP N-(2-(2-methoxyphenyl)-4-oxo-4h-chromen-6-yl)nicotinamide F... 9 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00410697 CHEMBL2165084 Bioactive [3-(3-carbamoylpyrrol-1-yl)phenyl] N-(6-phenylhexyl)carbamate
CFAMM00410695 CHEMBL2165080 Bioactive [3-(3-carbamoylpyrrol-1-yl)phenyl] N-[2-[2-(2,4-difluorophenoxy)ethoxy]ethyl]carbamate
CFAMM00410701 CHEMBL2165078 Bioactive [3-(3-carbamoylpyrrol-1-yl)phenyl] N-[2-[2-(4-fluorophenoxy)ethoxy]ethyl]carbamate
CFAMM00410694 CHEMBL2165083 Bioactive [3-(3-carbamoylpyrrol-1-yl)phenyl] N-undec-10-ynylcarbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24530 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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