CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11638
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform inhibitor N,N-dimethyl-1-[[2-(2-methylbenzimidazol-1-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]piperidin-4-amine family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00410733 Functional Category Bioactive
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Binder Superfamily 2
Class Class 3391

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Emedastine Family 5 115
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 8 53
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 9 11
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 8 11
Deoxycytidine kinase inhibitor AGN-PC-07Z9B3 family 2 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 8 6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 9
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 1
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-0A9RCZ family 7 7
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 1
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 9 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 9 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 5 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 7 2
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 6 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00410733 CHEMBL2165498 Bioactive N,N-dimethyl-1-[[2-(2-methylbenzimidazol-1-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]piperidin-4-amine
CFAMM00410732 CHEMBL2165499 Bioactive 2-methyl-2-[4-[[2-(2-methylbenzimidazol-1-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]propanamide
CFAMM00410731 CHEMBL2165500 Bioactive 4-[2-(2-ethylbenzimidazol-1-yl)-6-[(4-methylsulfonylpiperazin-1-yl)methyl]thieno[3,2-d]pyrimidin-4-yl]morpholine
CFAMM00410730 CHEMBL2165502 Bioactive 4-[6-[[2,2-dimethyl-4-(oxetan-3-yl)piperazin-1-yl]methyl]-2-(2-ethylbenzimidazol-1-yl)thieno[3,2-d]pyrimidin-4-yl]morpholine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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