CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11650
Family Name Melanin-concentrating hormone receptor 1 ligand 3-[(1S,4R,5S)-4-[(5-chloro-6-fluoro-1H-benzimidazol-2-yl)-[3-(4-methylpiperazin-1-yl)propyl]amino]-1-bicyclo[3.1.0]hexanyl]benzonitrile family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00410781 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 and Nociceptin receptor Binder Superfamily 2
Class Class 1016

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Mizolastine Family 14 603
Tryptase Inhibitor Babim Family 12 90
Dipeptidyl peptidase 4 Inhibitor (5-phenyl-3h-benzo[d]imidazol... 5 13
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 3
Transient receptor potential M8 protein ligand 2-[(E)-2-(oxan-... 5 3
Melanin-concentrating hormone receptor 1 ligand AGN-PC-00BSP9 ... 6 12
Melanin-concentrating hormone receptor 1 ligand 3-[(1R,3R,6S)-... 6 6
Melanin-concentrating hormone receptor 1 ligand 3-[(1R,3R,6S)-... 2 4
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00410781 CHEMBL216570 Bioactive 3-[(1S,4R,5S)-4-[(5-chloro-6-fluoro-1H-benzimidazol-2-yl)-[3-(4-methylpiperazin-1-yl)propyl]amino]-1-bicyclo[3.1.0]hexanyl]benzonitrile
CFAMM00410783 CHEMBL217761 Bioactive 4-[(1S,4R,5S)-4-[(5-chloro-6-fluoro-1H-benzimidazol-2-yl)-[3-(4-methylpiperazin-1-yl)propyl]amino]-1-bicyclo[3.1.0]hexanyl]benzonitrile
CFAMM00410782 CHEMBL383901 Bioactive 3-[(1S,4R,5S)-4-[(5,6-dichloro-1H-benzimidazol-2-yl)-[3-(4-methylpiperazin-1-yl)propyl]amino]-1-bicyclo[3.1.0]hexanyl]benzonitrile

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26391 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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