CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11652
Family Name Diacylglycerol O-acyltransferase 1 inhibitor 2-[4-[4-(7-aminopyrazolo[1,5-a]pyrimidin-6-yl)phenyl]cyclohexyl]acetic acid family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00410796 Functional Category Bioactive
Superfamily Progesterone receptor Ligand GSK-325971A Superfamily
Class Class 2684

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Zaleplon Family 6 589
C-reactive protein Inhibitor ISIS-CRP Family 4 105
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Vascular endothelial growth factor receptor 1 and Vascular end... 6 23
Metabotropic glutamate receptor 5 Ligand 3-(1-pyridin-2-yl-1h-... 3 6
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 63
Tyrosine-protein kinase Lck and Tyrosine-protein kinase HCK in... 8 7
Mitogen-activated protein kinase 13 inhibitor N-cyclopropyl-3-... 16 40
Adenosine receptor A3 and Adenosine receptor A2a ligand AGN-PC... 3 18
Adenosine receptor A3 ligand AGN-PC-07N4XX family 6 10
Adenosine receptor A3 ligand AGN-PC-07N4XY family 2 2
Adenosine receptor A3 and Adenosine receptor A1 ligand AGN-PC-... 5 1
Adenosine receptor A3 and Adenosine receptor A2a ligand SureCN... 8 7
Adenosine receptor A3 ligand SureCN6627522 family 3 2
Adenosine receptor A2a ligand AGN-PC-077RWY family 4 5
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 7 9
C-C chemokine receptor type 5 ligand AC1LA25C family 3 6
Prothrombin and Survival motor neuron protein inhibitor CHEMBL... 2 14
Nuclear receptor ROR-gamma and Mitogen-activated protein kinas... 1 10
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL1... 7 4
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 2 1
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 11 0
Vascular endothelial growth factor receptor 1 and Vascular end... 4 0
Tyrosine-protein kinase Mer and Tyrosine-protein kinase recept... 5 3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 2 inhibitor (2... 16 5
C-C chemokine receptor type 5 ligand (2R)-3-cyclobutyl-2-[(3S,... 2 0
Metabotropic glutamate receptor 2 ligand 3-(cyclopropylmethyl)... 1 1
Casein kinase II subunit alpha inhibitor 2pvj family 3 1
Tyrosine-protein kinase JAK2 inhibitor N-(3-methylphenyl)-5-(3... 2 4
Glucocorticoid receptor ligand 3-[1-(4-fluorophenyl)indazol-5-... 16 10
Cathepsin K inhibitor 4-[2,2-dimethylpropyl-[[4-(1,2,4-triazol... 2 1
Diacylglycerol O-acyltransferase 1 inhibitor 2-[4-[4-[5-(6-chl... 2 0
Corticotropin-releasing factor receptor 1 ligand 4-[7-(dipropy... 1 1
Fatty-acid amide hydrolase 1 and Liver carboxylesterase 1 inhi... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00410796 CHEMBL2165819 Bioactive 2-[4-[4-(7-aminopyrazolo[1,5-a]pyrimidin-6-yl)phenyl]cyclohexyl]acetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27525 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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