CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11654
Family Name Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha ligand Quinoline 16 family
No. of Seeds 10 No. of Other Members 2
Family Centroid CFAMM00295189 Functional Category Bioactive
Superfamily Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha Binder Superfamily 5
Class Class 78

Cousin Family NamesSeedsMembers
Muscarinic acetylcholine receptor M4 Ligand Tropicamide Family 3 73
Thromboxane A2 receptor Ligand Ridogrel Family 7 83
Indoleamine 2,3-dioxygenase 1 Inhibitor L-tryptophan Family 8 328
Proteinase-activated receptor 1 Ligand SCH-530348 Family 20 215
Dihydroorotate dehydrogenase Inhibitor Brequinar Family 9 122
Substance-P receptor Ligand GSK424887 Family 8 184
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(4... 4 21
Poly [ADP-ribose] polymerase 1 Inhibitor 3-ethenylquinoline-8-... 8 4
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 5-... 4 10
Mitogen-activated protein kinase 14 Inhibitor N-(4-fluorobenzy... 19 32
Glutamate receptor 1 Ligand Piriqualone Family 8 67
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 3 27
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Sodium-dependent dopamine transporter Inhibitor (+/-)-threo-n-... 4 12
Prostaglandin E2 receptor EP4 subtype and Prostaglandin D2 rec... 8 17
Tyrosine-protein kinase JAK2 and Tyrosine-protein kinase JAK1 ... 2 4
Dipeptidyl peptidase 4 inhibitor AGN-PC-09QKOM family 5 8
Prostaglandin D2 receptor 2 ligand 2-[1-(4-benzamidobenzoyl)is... 4 9
Egl nine homolog 1 inhibitor 2-[5-methyl-6-[[1-oxo-2-(4-phenyl... 4 3
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 7 0
Oxysterols receptor LXR-beta and Oxysterols receptor LXR-alpha... 2 1
Substance-P receptor ligand N-[[3,5-bis(trifluoromethyl)phenyl... 1 3
ATP-sensitive inward rectifier potassium channel 11 ligand N-[... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00410808 CHEMBL226461 Bioactive AGN-PC-046RUA

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26820 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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