CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11667
Family Name Aurora kinase A inhibitor Bisanilinopyrimidine, 6j family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00410930 Functional Category Bioactive
Superfamily Integrin alpha-4 Inhibitor CDP323 Superfamily
Class Class 898

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
Peptide deformylase, mitochondrial inhibitor folic acid analog... 59 98
Aurora kinase A Inhibitor MLN8054 Family 2 5
Casein kinase II subunit alpha Inhibitor CX-4945 Family 1 7
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
JAK Inhibitor Momelotinib Family 33 83
Proto-oncogene tyrosine-protein kinase Src Inhibitor PD166285 ... 6 70
Bacterial outer membrane Inhibitor HKI-9924129 Family 19 85
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 12 30
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-[(3,5... 28 18
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 6 9
Adenosine receptor A1 ligand AGN-PC-07PMLW family 6 4
Dihydrofolate reductase inhibitor AGN-PC-075RRH family 2 3
Hepatocyte growth factor receptor and Insulin receptor ligand ... 4 15
Dipeptidyl peptidase 4 inhibitor 3-[6-[(3R,4S)-3-amino-4-(2,4,... 3 7
Integrin beta-1 and Integrin alpha-5 inhibitor (2S)-2-[(2,6-di... 6 5
Type-1A angiotensin II receptor ligand 2-[[2-butyl-3-[(4-carbo... 2 4
Aurora kinase A and Cyclin-dependent kinase 4 inhibitor 2-[3-[... 1 0
Aurora kinase A inhibitor Bisanilinopyrimidine, 6i family 1 0
Aurora kinase A inhibitor 4-[[4-(2-chloroanilino)pyrimidin-2-y... 1 0
Leucine-rich repeat serine/threonine-protein kinase 2 inhibito... 2 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (4-am... 2 1
Non-receptor tyrosine-protein kinase TYK2 ligand AGN-PC-0D0YSZ... 10 0
Tyrosine-protein kinase JAK2 inhibitor 4-[[8-(1-propan-2-ylpyr... 5 6
C-C chemokine receptor type 5 ligand 4-[[5-[[4-[(5R)-5-(3-chlo... 1 0
Ephrin type-A receptor 3 and Tyrosine-protein kinase Fgr ligan... 1 3
Coagulation factor X inhibitor AGN-PC-078Y0S family 7 1
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5368289 f... 4 5
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5370042 f... 8 0
Integrin beta-1 and Integrin alpha-4 inhibitor SureCN5367895 f... 3 0
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-071H3F fa... 3 0
Integrin beta-1 and Integrin alpha-5 inhibitor 2-[(2,6-dimethy... 9 1
Integrin beta-1 and Integrin alpha-4 inhibitor (2S)-3-[4-[(2,6... 1 1
Diacylglycerol O-acyltransferase 1 inhibitor 2-[4-[4-(4-amino-... 2 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00410932 CHEMBL2170589 Bioactive 3-[[4-(2-chloroanilino)-5-fluoropyrimidin-2-yl]amino]benzoic acid
CFAMM00410930 CHEMBL2170436 Bioactive Bisanilinopyrimidine, 6j

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26190 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543