CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11668
Family Name Aurora kinase A inhibitor 4-[[4-(2-chloroanilino)pyrimidin-2-yl]amino]-2-hydroxybenzoic acid family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00410933 Functional Category Bioactive
Superfamily Prelamin-A/C and Aurora kinase A Binder Superfamily
Class Class 3526

Cousin Family NamesSeedsMembers
Prostaglandin G/H synthase 2 Inhibitor Niflumic Acid Family 7 119
Aurora kinase A Inhibitor MLN8054 Family 2 5
Casein kinase II subunit alpha Inhibitor CX-4945 Family 1 7
Proto-oncogene tyrosine-protein kinase Src Inhibitor PD166285 ... 6 70
Mitogen-activated protein kinase 8 Inhibitor 2-(2-phenoxypyrim... 12 30
5-hydroxytryptamine receptor 4 ligand AGN-PC-00GB52 family 5 2
Aurora kinase A inhibitor Bisanilinopyrimidine, 6i family 1 0
Aurora kinase A inhibitor Bisanilinopyrimidine, 6j family 2 1
C-C chemokine receptor type 5 ligand 4-[[5-[[4-[(5R)-5-(3-chlo... 1 0
Ephrin type-A receptor 3 and Tyrosine-protein kinase Fgr ligan... 1 3
Vascular endothelial growth factor receptor 2 ligand pyrimidin... 2 2
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-071H3F fa... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00410933 CHEMBL2170437 Bioactive 4-[[4-(2-chloroanilino)pyrimidin-2-yl]amino]-2-hydroxybenzoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27620 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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