CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11675
Family Name Lysine--tRNA ligase and Tyrosine-protein kinase Lyn inhibitor 2-[3-[[4-[(2,2-difluoro-3-oxo-4H-1,4-benzoxazin-6-yl)amino]-5-fluoropyrimidin-2-yl]amino]phenoxy]-N-methylacetamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00137678 Functional Category Bioactive
Superfamily Dihydrofolate reductase and Dual specificity protein kinase TTK Binder Superfamily
Class Class 831

Cousin Family NamesSeedsMembers
Tyrosine-protein kinase SYK Inhibitor R788 Family 3 7
AP26113 family 16 90
Platelet-derived growth factor receptor alpha and Fibroblast g... 3 47
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 1 0
Dihydrofolate reductase inhibitor AC1L9XPA family 6 5
Calcium/calmodulin-dependent protein kinase kinase 2 and Focal... 3 17
Insulin-like growth factor 1 receptor ligand 3qqu family 2 12
Ephrin type-B receptor 4 ligand SureCN5131922 family 4 0
Toll-like receptor 7 ligand 4-amino-1-[[6-(2-pyrrolidin-1-ylet... 2 5
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 5 7
Rho-associated protein kinase 1 and cAMP-dependent protein kin... 1 11
Epidermal growth factor receptor ligand N-[3-[7-[2-methoxy-4-(... 9 3
Tyrosine-protein kinase Lck inhibitor AGN-PC-0762WF family 2 0
Epidermal growth factor receptor ligand SureCN2989664 family 5 2
Cyclin-dependent kinase 4 and Cyclin-dependent kinase 2 inhibi... 1 3
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 3 5
Vascular endothelial growth factor receptor 2 ligand SureCN472... 1 0


External ID

Functional Category

Molecule Name

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



54900 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543