CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11676
Family Name Sodium/hydrogen exchanger 1 inhibitor 4-(1-acetylpiperidin-4-yl)-N-(diaminomethylidene)-3-(trifluoromethyl)benzamide family
No. of Seeds 3 No. of Other Members 19
Family Centroid CFAMM00411006 Functional Category Bioactive
Superfamily Prothrombin and Trypsin-1 Binder Superfamily 7
Class Class 1635

Cousin Family NamesSeedsMembers
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Substance-P receptor ligand (3S,4S)-N-[[3,5-bis(trifluoromethy... 8 9


External ID

Functional Category

Molecule Name

CFAMM00410986 CHEMBL2170608 Bioactive N-(diaminomethylidene)-4-[1-(2-methoxyacetyl)piperidin-4-yl]-3-(trifluoromethyl)benzamide
CFAMM00411006 CHEMBL2170610 Bioactive 4-(1-acetylpiperidin-4-yl)-N-(diaminomethylidene)-3-(trifluoromethyl)benzamide
CFAMM00411005 CHEMBL2170611 Bioactive 4-(1-acetylpiperidin-4-yl)-N-(diaminomethylidene)-2-methyl-5-(trifluoromethyl)benzamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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