CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11696
Family Name Eukaryotic translation initiation factor 2-alpha kinase 3 inhibitor 1-[5-(4-aminofuro[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-2-(2,5-difluorophenyl)ethanone family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00411133 Functional Category Bioactive
Superfamily Peptide deformylase, mitochondrial and Serine/threonine-protein kinase Chk1 Binder Superfamily
Class Class 1877

Cousin Family NamesSeedsMembers
Peptide deformylase, mitochondrial Inhibitor Furo[2,3d]pyrimid... 2 10
Serine/threonine-protein kinase Chk1 Inhibitor N-(5,6-diphenyl... 9 100
Angiopoietin-1 receptor and Aurora kinase B ligand SureCN12658... 3 19
Glycogen synthase kinase-3 beta and Cyclin-dependent kinase 2 ... 2 3
Vascular endothelial growth factor receptor 1 and Receptor-typ... 2 11
Vascular endothelial growth factor receptor 1 ligand CHEMBL197... 1 2
Activated CDC42 kinase 1 inhibitor 6-(4-methylsulfonylphenyl)-... 2 0
Activated CDC42 kinase 1 inhibitor 6-[4-(2-morpholin-4-ylethox... 7 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00411132 CHEMBL2171137 Bioactive 1-[5-(4-aminofuro[3,2-c]pyridin-3-yl)-2,3-dihydroindol-1-yl]-2-(2,5-difluorophenyl)ethanone
CFAMM00411133 CHEMBL2171136 Bioactive 1-[5-(4-aminofuro[2,3-d]pyrimidin-5-yl)-2,3-dihydroindol-1-yl]-2-(2,5-difluorophenyl)ethanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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