CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11701
Family Name Vitamin D3 receptor ligand (3E,5E)-6-[3-[[3,4-bis(hydroxymethyl)phenyl]methoxy]phenyl]-1,1,1-trifluoro-2-(trifluoromethyl)octa-3,5-dien-2-ol family
No. of Seeds 2 No. of Other Members 4
Family Centroid CFAMM00411239 Functional Category Bioactive
Superfamily Tyrosinase Inhibitor Monobenzone Superfamily
Class Class 470

Cousin Family NamesSeedsMembers
Retinoic acid receptor Ligand naphthoic acid derivative Adapal... 2 264
Histamine H1 receptor Ligand Doxepin Family 8 89
Cannabinoid receptor 1 Ligand Marinol Family 32 454
Prostaglandin G/H synthase 2 Inhibitor Nabumetone Family 4 267
Signal transducer and activator of transcription 3 Inhibitor A... 5 249
Tyrosinase Inhibitor Monobenzone Family 6 197
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Salicin family 5 629
Sphingosine kinase 2 Inhibitor Phenoxodiol Family 24 682
NAD-dependent protein deacetylase sirtuin-1 Inhibitor SRT501 F... 19 88
Muscarinic acetylcholine receptor M1 Ligand GSK1034702 Family 7 148
Glucokinase Inhibitor R7201 Family 22 105
Multidrug resistance protein Inhibitor Curcumin I Family 19 278
TS-071 family 8 36
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(4-hexy... 9 86
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 Ligand... 4 26
Glucocorticoid receptor Ligand 1-methoxy-6-phenyl-6h-benzo[c]c... 2 22
Oestrogen receptor and Estrogen receptor beta Ligand 6-(4-hydr... 30 63
Abelson tyrosine-protein kinase 2 Inhibitor 3'',5''-dimethoxy-... 3 9
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 5 13
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Tubulin beta chain Inhibitor Combretastatin Family 3 5
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 214
NAD(P)H dehydrogenase [quinone] 1 Inhibitor NSC-106547 Family 3 65
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand 4-(1,... 3 31
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 37
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 5 8
Cannabinoid receptor 2 Ligand 2-(2-methoxybenzyl)-3h-benzo[f]c... 6 32
NAD(P)H dehydrogenase [quinone] 1 Inhibitor 4-hydroxy-3-(2-nap... 12 1
Indoleamine 2,3-dioxygenase 1 Inhibitor Naphthalene-1,4-diol F... 2 4
Tyrosine-protein phosphatase non-receptor type 1 and Neuramini... 10 2
Prostaglandin G/H synthase 1 Inhibitor 2-(2-methoxyphenyl)-1h-... 1 11
Tyrosinase Inhibitor 4-(6-hydroxynaphthalen-2-yl)benzene-1,3-d... 4 2
Prostaglandin G/H synthase 2 Inhibitor 3,4-dibenzyloxy-2'-hydr... 7 40
Sodium/glucose cotransporter 2 and Sodium/glucose cotransporte... 3 19
Cannabinoid receptor 1 and Cannabinoid receptor 2 ligand [(6aR... 1 0
Estrogen receptor beta and Estrogen receptor ligand SureCN4017... 3 5
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 7
Arachidonate 5-lipoxygenase inhibitor SureCN9727660 family 1 0
Arachidonate 5-lipoxygenase inhibitor SureCN9727677 family 1 2
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 17


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00411239 CHEMBL2171448 Bioactive (3E,5E)-6-[3-[[3,4-bis(hydroxymethyl)phenyl]methoxy]phenyl]-1,1,1-trifluoro-2-(trifluoromethyl)octa-3,5-dien-2-ol
CFAMM00411253 CHEMBL52374 Bioactive (3S,4R)-3-benzyl-7-[2-(hydroxymethyl)-5-(trifluoromethyl)phenyl]-3,4-dihydro-2H-chromen-4-ol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27432 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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