CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11703
Family Name Cdc2-related kinase inhibitor N-[6-(3,5-dimethylphenyl)-1-methylbenzimidazol-2-yl]cycloheptanecarboxamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00411259 Functional Category Bioactive
Superfamily cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor CI-930 Superfamily
Class Class 86

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand be... 4 301
Gamma-aminobutyric acid A receptor Ligand imidazopyridine deri... 5 644
5-hydroxytryptamine receptor Ligand Ramosetron Family 10 219
Histamine H1 receptor Ligand Mizolastine Family 14 603
Prothrombin Inhibitor Dabigatran Family 7 182
BIBT986 family 7 96
SB989 family 17 91
Tryptase Inhibitor Babim Family 12 90
cGMP-inhibited 3',5'-cyclic phosphodiesterase A Inhibitor CI-9... 3 13
Telomerase reverse transcriptase Inhibitor HOE-33258 Family 10 33
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Prothrombin and Cationic trypsin inhibitor (2S)-N-[(2S)-1-(1H-... 4 15
Acetylcholinesterase inhibitor SureCN251059 family 2 16
Histone deacetylase 1 and Histone deacetylase 8 inhibitor (E)-... 3 0
Melanin-concentrating hormone receptor 1 and Potassium voltage... 8 27
Melanin-concentrating hormone receptor 1 ligand AGN-PC-088XRP ... 2 10
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 7 10
Adenosine receptor A2a ligand AGN-PC-01LVXW family 2 25
Adenosine receptor A2a ligand SureCN14156209 family 3 2
C-C chemokine receptor type 5 ligand SureCN1573831 family 4 3
Peroxisome proliferator-activated receptor gamma ligand 1-[(4-... 7 29
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 3 3
D(4) dopamine receptor and D(2) dopamine receptor ligand 4-met... 13 8
Cellular tumor antigen p53 and Microtubule-associated protein ... 1 1
Coagulation factor X and Trypsin-1 inhibitor 1-(3-carbamimidoy... 4 1
Metabotropic glutamate receptor 2 ligand AGN-PC-09QJ9P family 2 7
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 21 32
Melanin-concentrating hormone receptor 1 ligand SureCN3334191 ... 4 7
C-C chemokine receptor type 5 ligand methyl N-cyano-4-[2-[(1R,... 8 8
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 10 14
Histamine H3 receptor and Potassium voltage-gated channel subf... 7 1
Histamine H3 receptor ligand SureCN2878688 family 8 1
Coagulation factor X and Coagulation factor IX inhibitor 5-ami... 9 4
Serine/threonine-protein kinase mTOR inhibitor 5-(2-amino-3H-b... 3 1
Neuronal acetylcholine receptor subunit beta-2 and Neuronal ac... 10 6
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 2 1
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 0
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
Melanocortin receptor 4 ligand AGN-PC-076AMT family 2 9
Orexin receptor type 2 and Orexin receptor type 1 ligand (2R)-... 12 16
Disintegrin and metalloproteinase domain-containing protein 17... 3 0
Disintegrin and metalloproteinase domain-containing protein 17... 10 4
Metabotropic glutamate receptor 2 ligand 8-(2,5-difluorophenyl... 6 2
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 3 0
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 2
Cyclin-dependent kinase 2 and Potassium voltage-gated channel ... 12 7
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-077RDJ family 15 1
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 5 1
B1 bradykinin receptor ligand AGN-PC-077LWO family 2 0
Platelet-derived growth factor receptor beta and Fibroblast gr... 10 0
Dipeptidyl peptidase 4 inhibitor SureCN5776796 family 1 0
Neuropeptide Y receptor type 5 ligand SureCN8149543 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00411259 CHEMBL2171517 Bioactive N-[6-(3,5-dimethylphenyl)-1-methylbenzimidazol-2-yl]cycloheptanecarboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27526 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543