CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11711
Family Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform inhibitor 1-[3-[[2-(2-ethylbenzimidazol-1-yl)-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl]azetidin-1-yl]-2-methylpropan-1-one family
No. of Seeds 7 No. of Other Members 2
Family Centroid CFAMM00411297 Functional Category Bioactive
Superfamily Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Binder Superfamily 2
Class Class 3391

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Emedastine Family 5 115
Adenosine receptor A3 and Dual specificity mitogen-activated p... 5 27
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 5 58
cGMP-specific 3',5'-cyclic phosphodiesterase and Potassium vol... 13 4
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN5... 6 24
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 4
Vascular endothelial growth factor receptor 2 and Mitogen-acti... 2 2
Sorbitol dehydrogenase inhibitor SureCN6335187 family 2 6
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 12
Cellular tumor antigen p53 and Thyrotropin receptor ligand CHE... 1 5
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 4 14
C-C chemokine receptor type 5 ligand methyl N-cyano-4-[2-[(1R,... 8 8
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 9 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 5 0
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 2 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00411294 CHEMBL2216903 Bioactive 1-[3-[2-(2-ethylbenzimidazol-1-yl)-9-methyl-6-morpholin-4-ylpurin-8-yl]oxyazetidin-1-yl]-2-methylpropan-1-one
CFAMM00411299 CHEMBL2171941 Bioactive 4-[2-(2-ethylbenzimidazol-1-yl)-9-methyl-8-[[(1S,4S)-2-(oxetan-3-yl)-2,5-diazabicyclo[2.2.1]heptan-5-yl]methyl]purin-6-yl]morpholine
CFAMM00411298 CHEMBL2171942 Bioactive 4-[2-(2-ethylbenzimidazol-1-yl)-9-methyl-8-[[3-(oxan-4-yl)azetidin-1-yl]methyl]purin-6-yl]morpholine
CFAMM00411297 CHEMBL2414301 Bioactive 1-[3-[[2-(2-ethylbenzimidazol-1-yl)-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl]azetidin-1-yl]-2-methylpropan-1-one
CFAMM00411296 CHEMBL2414300 Bioactive 1-[3-[[2-(2-ethylbenzimidazol-1-yl)-9-methyl-6-morpholin-4-ylpurin-8-yl]amino]azetidin-1-yl]-2-methylpropan-1-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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