CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11726
Family Name ALK tyrosine kinase receptor ligand 4-fluoro-N-[6-[[(2-hydroxy-2-methylpropyl)amino]methyl]-1-[4-(propan-2-ylcarbamoyl)cyclohexyl]benzimidazol-2-yl]benzamide family
No. of Seeds 6 No. of Other Members 2
Family Centroid CFAMM00411435 Functional Category Bioactive
Superfamily ALK tyrosine kinase receptor and Histone deacetylase 1 Binder Superfamily
Class Class 950

Cousin Family NamesSeedsMembers
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Phospholipase D1 Inhibitor Halopemide Family 17 111
Vasopressin V2 receptor Ligand VA-106483 Family 16 115
Cellular tumor antigen p53 and Beta-lactamase inhibitor CHEMBL... 1 53
C-C chemokine receptor type 3 and Sodium-dependent serotonin t... 12 2
ALK tyrosine kinase receptor and Leukocyte tyrosine kinase rec... 12 2
ALK tyrosine kinase receptor ligand 4-fluoro-N-[6-(piperidin-1... 10 7
ALK tyrosine kinase receptor ligand methyl 4-[2-benzamido-6-(p... 2 0
Proteinase-activated receptor 1 ligand 2-[[2-[[2-[acetyl-[(E)-... 6 15
Integrin beta-3 and Integrin alpha-V inhibitor AGN-PC-037CNR f... 5 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00411433 CHEMBL2172312 Bioactive 4-fluoro-N-[6-[[3-(2-hydroxypropan-2-yl)azetidin-1-yl]methyl]-1-[4-(propan-2-ylcarbamoyl)cyclohexyl]benzimidazol-2-yl]benzamide
CFAMM00411432 CHEMBL2172305 Bioactive 1-[[2-[(4-fluorobenzoyl)amino]-3-[4-(propan-2-ylcarbamoyl)cyclohexyl]benzimidazol-5-yl]methyl]piperidine-4-carboxylic acid
CFAMM00411431 CHEMBL2172309 Bioactive 4-fluoro-N-[6-[[(2S)-2-(2-hydroxypropan-2-yl)pyrrolidin-1-yl]methyl]-1-[4-(propan-2-ylcarbamoyl)cyclohexyl]benzimidazol-2-yl]benzamide
CFAMM00411430 CHEMBL2172336 Bioactive 1-[[2-[(4-fluorobenzoyl)amino]-3-[4-(propan-2-ylcarbamoyl)cyclohexyl]benzimidazol-5-yl]methyl]piperidine-2-carboxylic acid
CFAMM00411435 CHEMBL2172311 Bioactive 4-fluoro-N-[6-[[(2-hydroxy-2-methylpropyl)amino]methyl]-1-[4-(propan-2-ylcarbamoyl)cyclohexyl]benzimidazol-2-yl]benzamide
CFAMM00411434 CHEMBL2172310 Bioactive 4-fluoro-N-[6-[[3-(2-hydroxypropan-2-yl)pyrrolidin-1-yl]methyl]-1-[4-(propan-2-ylcarbamoyl)cyclohexyl]benzimidazol-2-yl]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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