CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11732
Family Name ALK tyrosine kinase receptor ligand 4-fluoro-N-[1-[4-(propan-2-ylcarbamoyl)cyclohexyl]-6-pyridin-2-yloxybenzimidazol-2-yl]benzamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00411461 Functional Category Bioactive
Superfamily Neuronal acetylcholine receptor subunit beta-2 and Neuronal acetylcholine receptor subunit alpha-4 Binder Superfamily 6
Class Class 1163

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase B-raf inhibitor diaryl urea an... 12 93
Gamma-secretase subunit APH-1B Inhibitor E2012 Family 3 67
RAF proto-oncogene serine/threonine-protein kinase Inhibitor R... 7 148
C-X-C chemokine receptor type 3 Ligand AMG-487 Family 28 73
Serine/threonine-protein kinase PLK1 and Serine/threonine-prot... 14 42
Hepatocyte growth factor receptor and Receptor-type tyrosine-p... 12 26
Thyroid hormone receptor beta and Ferritin light chain ligand ... 1 35
Melanocortin receptor 4 ligand AGN-PC-076AML family 3 24
cGMP-dependent 3',5'-cyclic phosphodiesterase and cAMP and cAM... 3 10
Growth hormone secretagogue receptor type 1 ligand 2-methyl-6-... 2 0
Smoothened homolog and Mitogen-activated protein kinase 14 inh... 7 11
Rho-associated protein kinase 1 inhibitor SureCN4007647 family 8 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 1
Angiopoietin-1 receptor and Vascular endothelial growth factor... 4 8
Glycogen synthase kinase-3 beta and Casein kinase I isoform ga... 3 0
Vascular endothelial growth factor receptor 2 and Serine/threo... 6 13
Vascular endothelial growth factor receptor 2 ligand 2-aminobe... 3 5
Angiopoietin-1 receptor and Vascular endothelial growth factor... 2 0
Vasopressin V1a receptor and Vasopressin V2 receptor ligand AG... 2 2
Cannabinoid receptor 2 ligand AGN-PC-03LKW5 family 24 5
RAF proto-oncogene serine/threonine-protein kinase inhibitor a... 8 6
Insulin-like growth factor 1 receptor ligand SureCN311483 family 3 0
RAF proto-oncogene serine/threonine-protein kinase inhibitor a... 5 0
Delta-type opioid receptor and Kappa-type opioid receptor liga... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00411461 CHEMBL2172337 Bioactive 4-fluoro-N-[1-[4-(propan-2-ylcarbamoyl)cyclohexyl]-6-pyridin-2-yloxybenzimidazol-2-yl]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27529 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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