CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1176
Family Name 5-hydroxytryptamine receptor 1A and D(2) dopamine receptor ligand ACMC-20mxer family
No. of Seeds 10 No. of Other Members 6
Family Centroid CFAMM00320331 Functional Category Bioactive with Natural Product
Superfamily Muscarinic acetylcholine receptor Ligand Methantheline Superfamily
Class Class 572

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Acolbifene family 10 115
5-hydroxytryptamine receptor 1A Ligand Robalzotan Family 9 41
Histamine H3 receptor Ligand UCL-2138 Family 23 172
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 7 22
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
5-hydroxytryptamine receptor 7 Ligand (r)-8-phenyl-n,n-dipropy... 9 14
Histamine H3 receptor ligand 1-(4-pentan-3-ylpiperazin-1-yl)-2... 1 1
D(4) dopamine receptor and D(3) dopamine receptor ligand 3-ben... 5 334
5-hydroxytryptamine receptor 1A ligand (3S)-3-[4-(7,9-dioxo-8-... 2 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 0


External ID

Functional Category

Molecule Name

CFAMM00320333 CHEMBL11265 Bioactive 8-[4-(5-methoxyspiro[2,4-dihydrochromene-3,2'-pyrrolidine]-1'-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione
CFAMM00320323 CHEMBL50722 Bioactive AGN-PC-073RN8
CFAMM00320322 CHEMBL417550 Bioactive AGN-PC-073RRN
CFAMM00320328 CHEMBL50993 Bioactive AGN-PC-073RWM
CFAMM00320331 CHEMBL11592 Bioactive ACMC-20mxer
CFAMM00320321 CHEMBL27763 Bioactive AGN-PC-00F9BB
CFAMM00320327 CHEMBL301060 Bioactive AGN-PC-04S91E
CFAMM00320320 CHEMBL422283 Bioactive AGN-PC-00FACN
CFAMM00320325 CHEMBL50188 Bioactive AGN-PC-073RME

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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