CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11787
Family Name Tyrosine-protein kinase JAK2 and Cytochrome P450 3A4 inhibitor 5-amino-N-[4-(3-chlorophenyl)-2-methyl-1,3-thiazol-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00411845 Functional Category Bioactive
Superfamily Cruzipain and Huntingtin Binder Superfamily 3
Class Class 4868

Cousin Family NamesSeedsMembers
Dipeptidyl peptidase 8 and Dipeptidyl peptidase 4 inhibitor Su... 5 13
Mitogen-activated protein kinase 14 and LIM domain kinase 1 in... 4 19
Adenosine receptor A3 ligand N-(5-methyl-2-phenylpyrazolo[4,3-... 5 8
Adenosine receptor A1 and Adenosine receptor A2a ligand 2-(4-a... 8 11
Tyrosine-protein kinase JAK2 inhibitor N-[2-(3-chlorophenyl)-5... 2 11
Prelamin-A/C inhibitor CHEMBL1472945 family 1 32
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QM1E family 8 15
Nociceptin receptor and Potassium voltage-gated channel subfam... 10 1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 3 11
Adenosine receptor A3 and Adenosine receptor A1 ligand CHEMBL1... 7 4
Somatostatin receptor type 5 and Somatostatin receptor type 2 ... 6 3
Aurora kinase B and Aurora kinase A inhibitor 4-amino-N-[3-[[(... 5 3
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 6 1
TGF-beta receptor type-1 and Mitogen-activated protein kinase ... 6 4
Tyrosine-protein kinase JAK2 inhibitor N-[3-(3-chlorophenyl)-1... 12 4
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 17 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 1 0
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-fluoro... 5 1
Tyrosine-protein kinase SYK inhibitor N-tert-butyl-2-(6-chloro... 2 0
Tyrosine-protein kinase JAK3 and Tyrosine-protein kinase JAK2 ... 12 3
Histone deacetylase 1 and Proto-oncogene tyrosine-protein kina... 4 0
Platelet-activating factor receptor ligand SureCN9378808 family 3 0
Glutamate racemase inhibitor 5-[5-but-2-ynyl-2-[(6-chloroquino... 9 8
Glutamate racemase inhibitor AGN-PC-077KKZ family 6 0
Glutamate racemase inhibitor AGN-PC-077KMZ family 6 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00411845 CHEMBL2178258 Bioactive 5-amino-N-[4-(3-chlorophenyl)-2-methyl-1,3-thiazol-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27512 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543