CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11805
Family Name Inosine-5'-monophosphate dehydrogenase inhibitor 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-[3-[(E)-N-methoxy-C-methylcarbonimidoyl]phenyl]propan-2-yl]urea family
No. of Seeds 3 No. of Other Members 5
Family Centroid CFAMM00411910 Functional Category Bioactive
Superfamily Inosine-5'-monophosphate dehydrogenase and Beta-lactamase Binder Superfamily
Class Class 3141

Cousin Family NamesSeedsMembers
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
Cannabinoid receptor 1 Ligand 1-(bis(4-chlorophenyl)methyl)-3-... 4 44
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 7 134
MO15-related protein kinase Pfmrk Inhibitor 2-chloro-n-(o-toly... 6 28
Inosine-5'-monophosphate dehydrogenase inhibitor 1-(3,4-dichlo... 1 1
Reverse transcriptase/RNaseH inhibitor (4S)-5-chloro-4-(2-cycl... 5 7
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 7 2
Reverse transcriptase/RNaseH inhibitor AC1L9SWL family 3 0


External ID

Functional Category

Molecule Name

CFAMM00411910 CHEMBL2178620 Bioactive 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-[3-[(E)-N-methoxy-C-methylcarbonimidoyl]phenyl]propan-2-yl]urea
CFAMM00411916 CHEMBL2178652 Bioactive 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-(3-prop-1-en-2-ylphenyl)propan-2-yl]urea
CFAMM00411914 CHEMBL2178644 Bioactive 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-[2-[3-[(E)-N-hydroxy-C-methylcarbonimidoyl]phenyl]propan-2-yl]urea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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