CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11821
Family Name Beta-secretase 1 and Beta-secretase 2 inhibitor SureCN5930118 family
No. of Seeds 15 No. of Other Members 30
Family Centroid CFAMM00412078 Functional Category Bioactive
Superfamily Beta-secretase 1 and Beta-secretase 2 Binder Superfamily 9
Class Class 3059

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Saquinavir Family 64 428
Somatostatin receptor type 2 ligand octapeptide Octreotide Family 27 172
Endothelin B receptor Ligand IRL-2500 Family 34 87
Beta-secretase 1 inhibitor 1-N-[(1S,2S)-3-(3,5-difluorophenyl)... 2 16
Interstitial collagenase and Matrilysin inhibitor (2S,3R)-N,2-... 3 1
High affinity nerve growth factor receptor and BDNF/NT-3 growt... 4 3
Pol polyprotein inhibitor AC1LAHQ9 family 8 15
Beta-secretase 1 and Cathepsin B inhibitor SureCN14347937 family 4 1
Substance-P receptor ligand (4R)-N-[(2R)-1-[benzyl(methyl)amin... 8 5
Beta-secretase 1 and Beta-secretase 2 inhibitor SureCN5929923 ... 2 2
Beta-secretase 1 and Beta-secretase 2 inhibitor SureCN4689966 ... 6 0
Beta-secretase 1 and Beta-secretase 2 inhibitor CHEMBL554146 f... 1 2


External ID

Functional Category

Molecule Name

CFAMM00412059 CHEMBL500275 Bioactive SureCN5929962
CFAMM00412040 CHEMBL558582 Bioactive SureCN5930465
CFAMM00412078 CHEMBL504197 Bioactive SureCN5930118
CFAMM00412064 CHEMBL554349 Bioactive SureCN5930482
CFAMM00412039 CHEMBL562555 Bioactive SureCN5930445
CFAMM00412044 CHEMBL2179138 Bioactive CHEMBL2179138
CFAMM00412070 CHEMBL2179136 Bioactive CHEMBL2179136
CFAMM00412038 CHEMBL2179137 Bioactive CHEMBL2179137
CFAMM00412043 CHEMBL2179139 Bioactive CHEMBL2179139
CFAMM00412056 CHEMBL560092 Bioactive CHEMBL560092
CFAMM00412069 CHEMBL2179140 Bioactive CHEMBL2179140
CFAMM00412037 CHEMBL561961 Bioactive SureCN5930035
CFAMM00412061 CHEMBL446972 Bioactive SureCN5930285
CFAMM00412054 CHEMBL560612 Bioactive SureCN5930228
CFAMM00412041 CHEMBL541757 Bioactive SureCN5930112

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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