CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11824
Family Name Histone deacetylase 6 and Histone deacetylase 1 inhibitor N-hydroxy-4-[[3-hydroxypropyl-[(2-methoxyphenyl)carbamoyl]amino]methyl]benzamide family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00412112 Functional Category Bioactive with Natural Product
Superfamily Prelamin-A/C and Menin Binder Superfamily 6
Class Class 2872

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Encainide F... 4 248
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-04UEH3 family 3 16
D(3) dopamine receptor and D(1A) dopamine receptor ligand N-[(... 6 14
D(3) dopamine receptor and D(2) dopamine receptor ligand (E)-N... 2 2
Prelamin-A/C and Survival motor neuron protein inhibitor CHEMB... 1 7
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Peptide deformylase inhibitor 2-[(2R)-2-(cyclopentylmethyl)-3-... 3 2
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 9 3
Bifunctional epoxide hydrolase 2 inhibitor 3-[4-[[4-(trifluoro... 5 22
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 6 11
Glucagon receptor and Gastric inhibitory polypeptide receptor ... 3 11
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 5 8
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 10
Bifunctional epoxide hydrolase 2 inhibitor 8-(2,6-difluorobenz... 4 1
Bifunctional epoxide hydrolase 2 inhibitor 8-(2-fluoro-5-hydro... 2 0
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00412112 CHEMBL2179249 Bioactive N-hydroxy-4-[[3-hydroxypropyl-[(2-methoxyphenyl)carbamoyl]amino]methyl]benzamide
CFAMM00412111 CHEMBL2179615 Bioactive N-hydroxy-4-[[2-(4-hydroxyphenyl)ethyl-[(2-methoxyphenyl)carbamoyl]amino]methyl]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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