CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11831
Family Name Scavenger receptor class B member 1 ligand 5-[9-[3-(4,6-dimethylpyrimidin-2-yl)oxypropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole family
No. of Seeds 7 No. of Other Members 3
Family Centroid CFAMM00412143 Functional Category Bioactive
Superfamily Scavenger receptor class B member 1 Binder Superfamily
Class Class 3548

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Atevirdine Family 4 55
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Scavenger receptor class B member 1 ligand methyl 9-[3-(4,6-di... 2 10
Scavenger receptor class B member 1 ligand 5-[9-[3-(3,5-difluo... 4 2
5-hydroxytryptamine receptor 1D ligand N-[4-[[5-[3-[2-(dimethy... 4 16
Scavenger receptor class B member 1 ligand 2-[9-[3-(4,6-dimeth... 1 0
Scavenger receptor class B member 1 ligand 5-[9-[3-(6-fluoro-1... 1 4
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 8 13
5-hydroxytryptamine receptor 6 ligand 2-[(2Z)-2-[3-[(3-methoxy... 1 11
Histone deacetylase 1 inhibitor (7S)-N-hydroxy-7-[[2-(5-methox... 1 2


External ID

Functional Category

Molecule Name

CFAMM00412148 CHEMBL2179500 Bioactive 5-[9-[3-(4,6-diethylpyrimidin-2-yl)oxypropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole
CFAMM00412147 CHEMBL2179485 Bioactive 9-[3-(4,6-diethylpyrimidin-2-yl)oxypropyl]-6-(3-methyl-1,2,4-oxadiazol-5-yl)-2,3-dihydro-1H-carbazol-4-one
CFAMM00412146 CHEMBL2179515 Bioactive 5-[9-[3-(3,5-difluorophenoxy)-2-fluoropropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole
CFAMM00412145 CHEMBL2179509 Bioactive 5-[9-[3-(3,4-difluorophenoxy)propyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole
CFAMM00412144 CHEMBL2179508 Bioactive 5-[9-[3-(3,5-difluorophenoxy)propyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole
CFAMM00412143 CHEMBL2179499 Bioactive 5-[9-[3-(4,6-dimethylpyrimidin-2-yl)oxypropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-3-methyl-1,2,4-oxadiazole
CFAMM00412149 CHEMBL2179501 Bioactive 3-methyl-5-[9-[3-[4-methyl-6-(trifluoromethyl)pyrimidin-2-yl]oxypropyl]-5,6,7,8-tetrahydrocarbazol-3-yl]-1,2,4-oxadiazole

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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