CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11833
Family Name Scavenger receptor class B member 1 ligand 9-[3-(4,6-diethylpyrimidin-2-yl)oxypropyl]-6-nitro-1,2,3,4-tetrahydrocarbazole family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00412156 Functional Category Bioactive
Superfamily Scavenger receptor class B member 1 and 5-hydroxytryptamine receptor 3B Binder Superfamily
Class Class 920

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1D Ligand Rizatriptan Family 7 460
Type-1 angiotensin II receptor Ligand Forasartan Family 3 253
Transient receptor potential cation channel subfamily V member... 15 457
Interleukin-12 subunit alpha Inhibitor STA-5326 Family 2 51
Tyrosine-protein kinase JAK2 Inhibitor INCB18424 Family 3 130
Aurora kinase B and Aurora kinase C Inhibitor GSK1070916 Family 53 580
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 35 270
JAK Inhibitor Momelotinib Family 33 83
PF-4217903 family 14 65
Corticotropin-releasing factor receptor 1 Ligand CP-154526 Family 9 29
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Prostaglandin G/H synthase 2 Inhibitor RWJ-67657 Family 3 33
Beta-secretase 1 Inhibitor 6-[2-(1h-indol-6-yl)ethyl]pyridin-2... 10 43
Steroid 17-alpha-hydroxylase/17,20 lyase and Aromatase Inhibit... 18 109
RAC-gamma serine/threonine-protein kinase and Rho-associated p... 16 46
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-phen... 8 11
Aromatase Inhibitor NSC-356781 Family 3 10
RAF proto-oncogene serine/threonine-protein kinase Inhibitor L... 219 124
Sodium-dependent serotonin transporter Inhibitor 6-nitroquipaz... 18 21
Type-2 angiotensin II receptor Ligand L-158809 Family 22 136
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-07ZB89 family 6 13
Neuronal acetylcholine receptor subunit alpha-7 and Potassium ... 4 7
Neuronal acetylcholine receptor subunit alpha-7 and Potassium ... 4 0
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 10 3
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 34 11
Serine/threonine-protein kinase mTOR and Phosphatidylinositol ... 46 9
Ephrin type-B receptor 4 ligand SureCN3289519 family 4 2
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 13
Platelet-activating factor receptor ligand AGN-PC-0750SP family 4 0
DNA-dependent protein kinase catalytic subunit and Tyrosine-pr... 2 10
Cyclin-dependent kinase 4 and G1/S-specific cyclin-D1 inhibito... 3 11
Serine/threonine-protein kinase B-raf inhibitor SureCN1013857 ... 9 3
Mitogen-activated protein kinase 14 inhibitor AGN-PC-03XQYG fa... 7 1
Glycogen synthase kinase-3 beta and Dual specificity protein k... 4 5
Mitogen-activated protein kinase 10 and Transcription factor A... 4 4
Serine/threonine-protein kinase pim-2 and Serine/threonine-pro... 9 2
Transient receptor potential cation channel subfamily V member... 4 0
TGF-beta receptor type-1 and TGF-beta receptor type-2 ligand S... 2 2
Casein kinase II subunit alpha and Homeodomain-interacting pro... 5 0
Aurora kinase A and Cyclin-dependent kinase 4 inhibitor 7-cycl... 1 0
Scavenger receptor class B member 1 ligand 3-[9-[3-(4,6-diethy... 1 0
Somatostatin receptor type 3 and Potassium voltage-gated chann... 3 3
TGF-beta receptor type-2 and Vascular endothelial growth facto... 2 1
Proto-oncogene tyrosine-protein kinase Src and Mast/stem cell ... 4 1
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 16 7
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 1-met... 2 0
Epidermal growth factor receptor ligand Pyrroloquinazoline der... 7 0
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 1 0
Type-1 angiotensin II receptor ligand SureCN7390271 family 2 1
Metabotropic glutamate receptor 1 ligand AGN-PC-00FV3S family 2 0
Mitogen-activated protein kinase 8 and Mitogen-activated prote... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00412155 CHEMBL2179507 Bioactive 9-[3-(4,6-diethylpyrimidin-2-yl)oxypropyl]-6-(tetrazol-1-yl)-1,2,3,4-tetrahydrocarbazole
CFAMM00412156 CHEMBL2179493 Bioactive 9-[3-(4,6-diethylpyrimidin-2-yl)oxypropyl]-6-nitro-1,2,3,4-tetrahydrocarbazole

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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