CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11835
Family Name 5-hydroxytryptamine receptor 1D ligand N-[4-[[5-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-1,2,4-oxadiazol-3-yl]methyl]phenyl]methanesulfonamide family
No. of Seeds 4 No. of Other Members 16
Family Centroid CFAMM00412158 Functional Category Bioactive
Superfamily 5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine receptor 6 Binder Superfamily
Class Class 1228

Cousin Family NamesSeedsMembers
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 4 3
Reverse transcriptase Inhibitor Atevirdine Family 4 55
Prostaglandin D2 receptor ligand 1-[3-[2-methoxy-6-[2-(4-metho... 6 16
Scavenger receptor class B member 1 ligand methyl 9-[3-(4,6-di... 2 10
Sphingosine 1-phosphate receptor 1 ligand 3-[5-[5-[3,5-bis(tri... 4 6
Sphingosine 1-phosphate receptor 1 ligand 3-(3H-benzimidazol-5... 2 3
Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate... 6 25
Scavenger receptor class B member 1 ligand 5-[9-[3-(3,5-difluo... 4 2
Scavenger receptor class B member 1 ligand 5-[9-[3-(4,6-dimeth... 7 3
Scavenger receptor class B member 1 ligand 5-[9-[3-(6-fluoro-1... 1 4
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 8 13
5-hydroxytryptamine receptor 1D ligand N-[4-[[5-[[3-(2-aminoet... 8 7
5-hydroxytryptamine receptor 6 ligand 2-[(2Z)-2-[3-[(3-methoxy... 1 11
Histone deacetylase 1 inhibitor (7S)-N-hydroxy-7-[[2-(5-methox... 1 2
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07CPKU family 1 3


External ID

Functional Category

Molecule Name

CFAMM00412160 CHEMBL39317 Bioactive 137403-12-4
CFAMM00412165 CHEMBL39435 Bioactive 4-[[5-[3-(2-aminoethyl)-1H-indol-5-yl]-1,2,4-oxadiazol-3-yl]methyl]-N-methylbenzenesulfonamide
CFAMM00412158 CHEMBL262652 Bioactive N-[4-[[5-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-1,2,4-oxadiazol-3-yl]methyl]phenyl]methanesulfonamide
CFAMM00412178 CHEMBL2179502 Bioactive N,N-dimethyl-3-[6-(3-methyl-1,2,4-oxadiazol-5-yl)-1,2,3,4-tetrahydrocarbazol-9-yl]propane-1-sulfonamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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