CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11846
Family Name Peroxisome proliferator-activated receptor gamma ligand NSI family
No. of Seeds 5 No. of Other Members 3
Family Centroid CFAMM00412216 Functional Category Bioactive
Superfamily Integrin beta-3 Inhibitor L-756568 Superfamily
Class Class 82

Cousin Family NamesSeedsMembers
Cysteinyl leukotriene receptor 1 Ligand Zafirlukast Family 48 78
Histamine H3 receptor and Cytochrome P450 2D6 ligand AGN-PC-00... 18 32
Cysteinyl leukotriene receptor 1 ligand 1-[[4-[(2-chlorophenyl... 4 0
Prostaglandin E2 receptor EP3 subtype ligand (E)-N-(3,4-difluo... 3 3


External ID

Functional Category

Molecule Name

CFAMM00412219 CHEMBL218231 Bioactive N-(4-fluorophenyl)sulfonyl-3-(4-methoxyphenyl)-1-[[3-(trifluoromethyl)phenyl]methyl]indole-2-carboxamide
CFAMM00412216 CHEMBL376627 Bioactive NSI
CFAMM00412222 CHEMBL221580 Bioactive 3-(4-methoxyphenyl)-N-methylsulfonyl-1-[[3-(trifluoromethyl)phenyl]methyl]indole-2-carboxamide
CFAMM00412215 CHEMBL218258 Bioactive methyl 2-[[3-(4-methoxyphenyl)-1-[[3-(trifluoromethyl)phenyl]methyl]indole-2-carbonyl]sulfamoyl]benzoate
CFAMM00412221 CHEMBL217962 Bioactive 3-(4-methoxyphenyl)-N-(2-methylphenyl)sulfonyl-1-[[3-(trifluoromethyl)phenyl]methyl]indole-2-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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