CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11850
Family Name 5-hydroxytryptamine receptor 3A ligand 5-hydroxy-1-methyl-N-[(1S,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide family
No. of Seeds 4 No. of Other Members 2
Family Centroid CFAMM00412251 Functional Category Bioactive
Superfamily Cannabinoid receptor 2 and 5-hydroxytryptamine receptor 4 Binder Superfamily
Class Class 4038

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
Mitogen-activated protein kinase 12 Inhibitor ARRY-797 Family 13 41
Coagulation factor X Inhibitor Apixaban Family 34 52
TGF-beta receptor type-1 Ligand LY2157299 Family 13 56
Adenosine receptor A3 Ligand 2-benzyl-2h-pyrazolo[3,4-c]quinol... 3 11
Orexin receptor type 2 and Orexin receptor type 1 ligand AGN-P... 7 19
5-hydroxytryptamine receptor 2A ligand AGN-PC-04RTMN family 7 5
5-hydroxytryptamine receptor 3A ligand SureCN8035577 family 5 4
Serine/threonine-protein kinase 17A and Myosin light chain kin... 3 7
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 4 1
5-hydroxytryptamine receptor 3A ligand 1-[4-[[7-(diethylamino)... 2 4
5-hydroxytryptamine receptor 4 ligand N-[(1R,5S)-8-[2-hydroxy-... 4 0
Cathepsin K and Cathepsin B inhibitor (1R,2R)-N-(1-cyanocyclop... 2 1
5-hydroxytryptamine receptor 4 ligand 4-[2-[4-[[(1-propan-2-yl... 1 1
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand N-(1-... 1 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 7-met... 2 1
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 1 0
Adenosine receptor A3 and Adenosine receptor A1 ligand 2-(3-me... 2 10
Hydroxycarboxylic acid receptor 2 and Cytochrome P450 2C9 liga... 2 7
72 kDa type IV collagenase and Matrix metalloproteinase-9 inhi... 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00412255 CHEMBL599011 Bioactive 7-hydroxy-1-methyl-N-[(1S,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide
CFAMM00412253 CHEMBL2179704 Bioactive N-[[1-[2-(4-hydroxyphenyl)ethyl]piperidin-4-yl]methyl]-1-propan-2-ylindazole-3-carboxamide;hydrochloride
CFAMM00412251 CHEMBL598804 Bioactive 5-hydroxy-1-methyl-N-[(1S,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide
CFAMM00412256 CHEMBL596951 Bioactive 1-methyl-N-[(1S,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-4-oxo-2H-indazole-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

22932 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543