CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1187
Family Name Histone deacetylase 1 and Histone deacetylase 2 inhibitor AGN-PC-074YF8 family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00320410 Functional Category Bioactive
Superfamily Cathepsin B and Cathepsin K Inhibitor L-006235-1 Superfamily
Class Class 804

Cousin Family NamesSeedsMembers
Prothrombin Inhibitor RWJ-50353 Family 11 95
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor 7-me... 2 45
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
C-C chemokine receptor type 4 Ligand 4-tert-butyl-n-o-tolylthi... 4 7
Metabotropic glutamate receptor 5 Ligand 3-chloro-n-(4-methylt... 2 12
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor 7-me... 3 14
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 4 3
Adenosine receptor A1 Ligand N-(4-phenyl-thiazol-2-yl)-benzami... 5 2
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-264... 6 32
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(5-b... 3 9
Adenosine receptor A1 Ligand 4-nitro-n-(4-phenyl-thiazol-2-yl)... 2 38
Neuropeptide Y receptor type 5 ligand 2-phenyl-1-[(1R,5S)-6-[[... 9 11
Protease and Capsid scaffolding protein inhibitor AC1LAC7K family 2 5
Neuropeptide Y receptor type 5 ligand N-[5-[(9-fluoro-5,6-dihy... 7 7
Mitogen-activated protein kinase 14 inhibitor N-[4-[2-ETHYL-4-... 4 5
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-[4-(4-phenyl-1,3-t... 3 4
Suppressor of tumorigenicity 14 protein and Serine protease he... 6 0
Cathepsin K and Cathepsin L1 inhibitor (2R)-N-(cyanomethyl)-4-... 2 1
Cholinesterase and Acetylcholinesterase inhibitor 3-[ethyl-[3-... 6 9
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 8 1
Sphingosine kinase 1 and Sphingosine kinase 2 inhibitor (2R,4S... 9 8
Histone deacetylase 1 inhibitor N',N'-bis[2-(1,3-benzothiazol-... 2 0
Neuropeptide Y receptor type 5 ligand [4-[[(9-fluoro-5,6-dihyd... 3 1
Neuropeptide Y receptor type 5 ligand 2-(dimethylamino)-1-[4-[... 10 5
Neuropeptide Y receptor type 5 ligand 1-[4-[[(9-fluoro-5,6-dih... 11 0
Integrin beta-3 and Integrin alpha-IIb inhibitor 4-[[4-(4-carb... 4 2
Proto-oncogene tyrosine-protein kinase LCK and Tyrosine-protei... 3 9
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 2 0
Membrane primary amine oxidase inhibitor N-[4-[2-[4-(diaminome... 5 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00320410 CHEMBL112984 Bioactive AGN-PC-074YF8
CFAMM00320415 CHEMBL113033 Bioactive AGN-PC-074YHC

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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