CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11871
Family Name cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A inhibitor 5,8-dimethyl-2-[2-(2-methyl-5-thiophen-3-yl-1,2,4-triazol-3-yl)ethyl]-[1,2,4]triazolo[1,5-a]pyridine family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00412366 Functional Category Bioactive
Superfamily cAMP and Prelamin-A/C Binder Superfamily
Class Class 3083

Cousin Family NamesSeedsMembers
Corticotropin-releasing factor receptor 1 Ligand R121919 Family 26 84
Prothrombin and Histone-lysine N-methyltransferase 2A inhibito... 1 7
Serine/threonine-protein kinase Chk1 and Cyclin-A2 inhibitor S... 1 1
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 12 7
Histamine H3 receptor ligand 2-(3-methyl-[1,2,4]triazolo[4,3-a... 1 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 1
Serine/threonine-protein kinase pim-1 and Serine/threonine-pro... 3 6
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 2
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 4 5
Glycogen synthase kinase-3 beta inhibitor pyrazolopyrimidine d... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00412366 CHEMBL2180416 Bioactive 5,8-dimethyl-2-[2-(2-methyl-5-thiophen-3-yl-1,2,4-triazol-3-yl)ethyl]-[1,2,4]triazolo[1,5-a]pyridine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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