CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11873
Family Name cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A inhibitor 5,8-dimethyl-2-[2-(1-methyl-2-thiophen-2-ylimidazol-4-yl)ethyl]-[1,2,4]triazolo[1,5-a]pyrazine family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00412379 Functional Category Bioactive
Superfamily cAMP and Survival motor neuron protein Binder Superfamily
Class Class 3366

Cousin Family NamesSeedsMembers
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-(4-e... 2 5
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-chlo... 11 20
Adenosine receptor A1 and Adenosine receptor A2a Ligand 2-ethy... 2 2
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 55
NADH-ubiquinone oxidoreductase chain 3 Inhibitor 6-thiophen-3-... 2 0
5-hydroxytryptamine receptor 6 ligand 6-chloro-5-[1-(1-methylp... 9 0
Mitogen-activated protein kinase 10 and Mitogen-activated prot... 2 18
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 7 21
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 2
Methionine aminopeptidase 2 inhibitor SureCN5376630 family 1 0
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 2 1
Type-1A angiotensin II receptor and Type-1B angiotensin II rec... 2 2
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 0
Adenosine receptor A2a and Adenosine receptor A2b ligand SureC... 4 5
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 1 0
Corticotropin-releasing factor receptor 1 ligand 2-[1-[1-[4-ni... 2 1
Inhibitor of nuclear factor kappa-B kinase subunit beta and In... 3 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00412379 CHEMBL2180418 Bioactive 5,8-dimethyl-2-[2-(1-methyl-2-thiophen-2-ylimidazol-4-yl)ethyl]-[1,2,4]triazolo[1,5-a]pyrazine
CFAMM00412380 CHEMBL2180419 Bioactive 5,8-dimethyl-2-[2-(2-thiophen-2-yl-1H-imidazol-5-yl)ethyl]-[1,2,4]triazolo[1,5-a]pyrazine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27759 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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