CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11880
Family Name cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A inhibitor 2-methyl-3-[[4-(oxan-4-yloxy)-6-pyrrolidin-1-ylpyrimidin-2-yl]methoxy]quinoxaline family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00412398 Functional Category Bioactive
Superfamily D(4) dopamine receptor and D(2) dopamine receptor Binder Superfamily
Class Class 3054

Cousin Family NamesSeedsMembers
Platelet-derived growth factor receptor Ligand CP-868596 Family 3 91
D(2) dopamine receptor and D(3) dopamine receptor Ligand [2-(1... 17 100
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 22
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 11
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 10
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 14
Cellular tumor antigen p53 and Prelamin-A/C inhibitor CHEMBL14... 2 11
Neuropeptide Y receptor type 1 ligand 1-[3-[1-(cyclohexylmethy... 15 9
Cathepsin K and Cathepsin L1 inhibitor CHEBI:43424 family 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 16 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 0
Dual specificity protein kinase TTK inhibitor 6-N-cyclohexyl-2... 12 2
5-hydroxytryptamine receptor 1A and Gonadotropin-releasing hor... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00412400 CHEMBL2180440 Bioactive 2-methyl-3-[(E)-2-[4-(oxan-4-yloxy)-6-pyrrolidin-1-ylpyrimidin-2-yl]ethenyl]quinoxaline
CFAMM00412399 CHEMBL2180442 Bioactive 2-methyl-3-[[6-(oxan-4-yloxy)-2-pyrrolidin-1-ylpyrimidin-4-yl]methoxy]quinoxaline
CFAMM00412398 CHEMBL2180443 Bioactive 2-methyl-3-[[4-(oxan-4-yloxy)-6-pyrrolidin-1-ylpyrimidin-2-yl]methoxy]quinoxaline

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27423 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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