CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11890
Family Name cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A inhibitor 6-cyclopropyl-N-(2-pyridin-2-yl-1,3-thiazol-5-yl)-3-(pyrimidin-5-ylamino)pyridine-2-carboxamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00412441 Functional Category Bioactive
Superfamily cAMP and Prelamin-A/C Binder Superfamily 2
Class Class 1642

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Aurora kinase B and Aurora kinase A Inhibitor CYC116 Family 16 135
Poly [ADP-ribose] polymerase 1 Inhibitor N-(4-phenylthiazol-2-... 6 150
Adenosine receptor A2b and Adenosine receptor A2a ligand SureC... 1 26
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 2 1
Receptor tyrosine-protein kinase erbB-2 ligand AGN-PC-07ZDR2 f... 7 33
Neuropeptide Y receptor type 5 ligand 2-phenyl-1-[(1R,5S)-6-[[... 9 11
Thyroid hormone receptor beta and Ferritin light chain ligand ... 3 10
Metabotropic glutamate receptor 5 ligand 5-methyl-N-(4-methyl-... 1 2
Metabotropic glutamate receptor 5 ligand 2-methyl-N-(6-methylp... 1 8
Serine/threonine-protein kinase Chk1 inhibitor 2-(1,3-dihydroi... 2 5
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-00A4QJ family 12 6
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 5 0
Methionine aminopeptidase and Methionine aminopeptidase 1 inhi... 3 7
Histone deacetylase 1 inhibitor SureCN1066177 family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00412441 CHEMBL2180800 Bioactive 6-cyclopropyl-N-(2-pyridin-2-yl-1,3-thiazol-5-yl)-3-(pyrimidin-5-ylamino)pyridine-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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