CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11891
Family Name cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A inhibitor [1-[3-[4-(1,3-benzothiazol-2-ylamino)phenoxy]pyrazin-2-yl]piperidin-4-yl]methanol family
No. of Seeds 5 No. of Other Members 6
Family Centroid CFAMM00412442 Functional Category Bioactive
Superfamily Glucokinase and cAMP Binder Superfamily
Class Class 834

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 42 32
Hydroxycarboxylic acid receptor 2 Ligand MBX-2982 Family 1 1
Rho-associated protein kinase 2 inhibitor SureCN13457044 family 1 17
Aurora kinase A inhibitor AGN-PC-00BCUF family 16 43
Inositol monophosphatase 1 and Microtubule-associated protein ... 1 12
Growth hormone secretagogue receptor type 1 ligand 6-(1,3-benz... 3 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
P2Y purinoceptor 1 inhibitor N-[2-(2-tert-butylphenoxy)pyridin... 2 19
P2Y purinoceptor 1 inhibitor N-[2-(2-tert-butylphenoxy)pyridin... 6 3
Adenosine receptor A2a and Adenosine receptor A1 ligand 2-(3-c... 3 3
Potassium-transporting ATPase alpha chain 1 and Potassium-tran... 2 11
Glucokinase inhibitor 4-methyl-N-[3-phenylmethoxy-5-(pyridin-2... 1 8
Cysteinyl leukotriene receptor 1 and Platelet-activating facto... 1 1
Nuclear receptor ROR-gamma and Neuropeptide S receptor ligand ... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00412446 CHEMBL2206226 Bioactive 1-[3-[4-(1,3-benzothiazol-2-ylamino)phenoxy]pyrazin-2-yl]piperidine-4-carboxylic acid
CFAMM00412444 CHEMBL2206224 Bioactive 2-[1-[3-[4-(1,3-benzothiazol-2-ylamino)phenoxy]pyrazin-2-yl]piperidin-4-yl]propan-2-ol
CFAMM00412443 CHEMBL2206223 Bioactive 1-[1-[3-[4-(1,3-benzothiazol-2-ylamino)phenoxy]pyrazin-2-yl]piperidin-4-yl]ethanol
CFAMM00412442 CHEMBL2206221 Bioactive [1-[3-[4-(1,3-benzothiazol-2-ylamino)phenoxy]pyrazin-2-yl]piperidin-4-yl]methanol
CFAMM00412448 CHEMBL2180805 Bioactive N-[4-(3-morpholin-4-ylpyridin-2-yl)oxyphenyl]-1,3-benzothiazol-2-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27527 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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