CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11894
Family Name Integrin beta-3 and Integrin alpha-V inhibitor 2-[(1R,5S,11S,15S)-17-benzyl-5-[3-(diaminomethylideneamino)propyl]-3,6,9,12,16,18-hexaoxo-4,7,10,13,17,19-hexazabicyclo[13.2.2]nonadecan-11-yl]acetic acid family
No. of Seeds 8 No. of Other Members 2
Family Centroid CFAMM00184862 Functional Category Bioactive
Superfamily Integrin alpha-V and Integrin beta-3 Binder Superfamily
Class Class 260

Cousin Family NamesSeedsMembers
Integrin alpha-V and Integrin beta-3 Inhibitor C[rgd-(s)-alpha... 19 95
Neuromedin-K receptor Ligand Senktide Family 15 22
Prothrombin Inhibitor D-leucyl-n-(4-carbamimidoylbenzyl)-l-pro... 13 44
Cathepsin F and Cruzipain Inhibitor WRR-99 Family 13 131
Integrin alpha-V and Integrin beta-3 Inhibitor Cyclo-[-arg-gly... 5 38
Integrin beta-3 Inhibitor Sibrafiban Family 4 6
Integrin beta-3 Inhibitor DMP-728 Family 3 0
Integrin beta-3 Inhibitor SKF-107260 Family 5 8
Beta-secretase 1 Inhibitor Glu-leu-asp-leu-(choh-ch2)-ala-ala-... 15 11
Chymase Inhibitor Chymostatin Family 2 3
Histone deacetylase 1 and Histone deacetylase 4 Inhibitor Azum... 3 10
Integrin alpha-V Inhibitor C[rgdf-(3s)-carboxymorpholine] Family 10 2
Caspase-4 and Cathepsin D Inhibitor Grassystatin A Family 24 6
Genome polyprotein Inhibitor Acasp-glu-met-glu-cha-cys Family 3 6
Mu-type opioid receptor and Nociceptin receptor Ligand Nocicep... 35 5
Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-3-[... 13 17
Tryptase alpha/beta-1 and Tryptase delta inhibitor (2S,3R)-1-b... 3 4
NS3 and Non-structural protein 4A inhibitor (4S)-4-[[(2S)-3-ca... 1 1
Integrin alpha-V and Integrin beta-5 inhibitor 2-[(2S,5R,8S,11... 2 1
Integrin beta-3 and Integrin alpha-IIb inhibitor (3R,6S,12S)-6... 7 0
Angiotensin-converting enzyme inhibitor SureCN7263641 family 2 11
Ribonucleoside-diphosphate reductase large subunit and Ribonuc... 1 0
NS3 inhibitor 6-[[(2S)-1-[[(2S)-1-[(2S)-2-[[1-(cyclopropylamin... 2 0
Bcl-2-like protein 1 inhibitor CHEMBL501005 family 2 2
4'-phosphopantetheinyl transferase ffp and Beta-lactamase inhi... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00412490 CHEMBL2180974 Bioactive 2-[(1R,5S,11S,15S)-17,19-dibenzyl-5-[3-(diaminomethylideneamino)propyl]-3,6,9,12,16,18-hexaoxo-4,7,10,13,17,19-hexazabicyclo[13.2.2]nonadecan-11-yl]acetic acid
CFAMM00412489 CHEMBL2180975 Bioactive 2-[(1S,5S,11S,15S)-19-benzyl-5-[3-(diaminomethylideneamino)propyl]-3,6,9,12,16,18-hexaoxo-4,7,10,13,17,19-hexazabicyclo[13.2.2]nonadecan-11-yl]acetic acid
CFAMM00412487 CHEMBL2180979 Bioactive 2-[(1S,5S,11S,15R)-17,19-dibenzyl-5-[3-(diaminomethylideneamino)propyl]-3,6,9,12,16,18-hexaoxo-4,7,10,13,17,19-hexazabicyclo[13.2.2]nonadecan-11-yl]acetic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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