CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11902
Family Name G-protein coupled bile acid receptor 1 ligand (4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,5-dichlorophenoxy)pyridin-3-yl]methanone family
No. of Seeds 10 No. of Other Members 13
Family Centroid CFAMM00412524 Functional Category Bioactive
Superfamily G-protein coupled bile acid receptor 1 Binder Superfamily
Class Class 6

Cousin Family NamesSeedsMembers
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
Reverse transcriptase/RNaseH inhibitor AC1LALKM family 2 19
Histamine H3 receptor ligand SureCN3057575 family 4 3
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 2
Sodium channel protein type 10 subunit alpha and Sodium channe... 1 1
Survival motor neuron protein and Lysine-specific demethylase ... 1 1
Ceramide glucosyltransferase and Cytochrome P450 3A4 inhibitor... 10 15
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 2 7
C-C chemokine receptor type 5 ligand N-[(3R)-3-[4-[4-methoxy-N... 13 1
Growth hormone secretagogue receptor type 1 and Potassium volt... 2 0
G-protein coupled bile acid receptor 1 ligand (4-cyclopropyl-2... 2 1
G-protein coupled bile acid receptor 1 ligand (4-cyclopropyl-2... 1 2
Motilin receptor ligand SureCN2768193 family 2 1
Alpha-2C adrenergic receptor and Alpha-2B adrenergic receptor ... 6 1
Acyl-CoA desaturase inhibitor 3-[[2-[4-(2-chlorophenoxy)piperi... 8 7


External ID

Functional Category

Molecule Name

CFAMM00412525 CHEMBL2181238 Bioactive [4-(2,5-dichlorophenoxy)pyridin-3-yl]-(4-prop-2-enyl-2,3-dihydroquinoxalin-1-yl)methanone
CFAMM00412524 CHEMBL2181239 Bioactive (4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,5-dichlorophenoxy)pyridin-3-yl]methanone
CFAMM00412531 CHEMBL2181246 Bioactive [2-(2,5-dichlorophenoxy)pyridin-3-yl]-(3,4-dihydro-2H-quinolin-1-yl)methanone
CFAMM00412530 CHEMBL2181227 Bioactive (4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,4,5-trichlorophenoxy)pyridin-3-yl]methanone
CFAMM00412523 CHEMBL2181235 Bioactive [4-(2,5-dichlorophenoxy)pyridin-3-yl]-(4-ethyl-2,3-dihydroquinoxalin-1-yl)methanone
CFAMM00412521 CHEMBL2181230 Bioactive (4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,5-dichloro-4-ethylphenoxy)pyridin-3-yl]methanone
CFAMM00412522 CHEMBL2181236 Bioactive [4-(2,5-dichlorophenoxy)pyridin-3-yl]-(4-propyl-2,3-dihydroquinoxalin-1-yl)methanone
CFAMM00412528 CHEMBL2181229 Bioactive (4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,5-dichloro-4-methylphenoxy)pyridin-3-yl]methanone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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