CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11903
Family Name G-protein coupled bile acid receptor 1 ligand (4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,5-dimethylphenoxy)pyridin-3-yl]methanone family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00412536 Functional Category Bioactive with Natural Product
Superfamily Reverse transcriptase/RNaseH and Prelamin-A/C Binder Superfamily
Class Class 2593

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 12 Inhibitor ARRY-797 Family 13 41
Histamine H3 receptor Ligand GSK239512 Family 2 65
Calcium-activated potassium channel subunit alpha-1 Ligand AVE... 3 284
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
Histamine H3 receptor and Potassium voltage-gated channel subf... 5 2
Histamine H3 receptor and Potassium voltage-gated channel subf... 3 2
Neuronal acetylcholine receptor subunit beta-4 and Neuronal ac... 1 0
Somatostatin receptor type 5 ligand AGN-PC-080TDB family 10 14
Somatostatin receptor type 5 ligand AGN-PC-088VSK family 2 3
Potassium voltage-gated channel subfamily H member 2 and Kappa... 5 33
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 19
Renin inhibitor [2-(3-fluoro-2,6-dimethylphenoxy)-1-phenylpyrr... 5 12
Ceramide glucosyltransferase and Cytochrome P450 3A4 inhibitor... 10 15
Growth hormone secretagogue receptor type 1 and Potassium volt... 2 0
Histamine H3 receptor ligand 6-[[2-[2-[(2R)-2-methylpyrrolidin... 2 0
G-protein coupled bile acid receptor 1 ligand (4-cyclopropyl-2... 10 13
G-protein coupled bile acid receptor 1 ligand (4-cyclopropyl-2... 1 2
Motilin receptor ligand SureCN2768193 family 2 1
Motilin receptor ligand SureCN2765637 family 1 1
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00412534 CHEMBL2181228 Bioactive (4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,4,5-trimethylphenoxy)pyridin-3-yl]methanone
CFAMM00412536 CHEMBL2181226 Bioactive (4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)-[4-(2,5-dimethylphenoxy)pyridin-3-yl]methanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26824 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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