CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11906
Family Name Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-PC-00AVLQ family
No. of Seeds 7 No. of Other Members 6
Family Centroid CFAMM00412548 Functional Category Bioactive
Superfamily Corticosteroid 11-beta-dehydrogenase isozyme 1 and Lethal factor Binder Superfamily
Class Class 960

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 16 295
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Dipeptidyl peptidase 4 Inhibitor Nvp-dpp728 Family 11 42
Class II cytokine receptor Ligand IL-10 Family 7 45
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
D(2) dopamine receptor and D(3) dopamine receptor Ligand Azape... 7 102
Calcitonin gene-related peptide type 1 receptor Ligand Isomer ... 30 31
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor (2R)-... 1 0
Integrin beta-3 and Integrin alpha-V inhibitor SureCN3888804 f... 11 13
Prothrombin and Cationic trypsin inhibitor tert-butyl N-[(2R)-... 4 3
Integrin beta-3 and Integrin alpha-V inhibitor (3S)-3-[[2-[6-m... 13 12
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 2 1
Integrin beta-3 and Integrin alpha-V inhibitor SureCN6359092 f... 9 5
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 3 1
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 1 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor SureC... 6 0
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 2
Integrin alpha-V and Integrin beta-6 inhibitor 3-[[2-[4-[(4-me... 4 3
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-(5-... 4 0
Corticosteroid 11-beta-dehydrogenase isozyme 1 and Corticoster... 2 0
Platelet-activating factor receptor ligand SureCN9853140 family 3 3
Transient receptor potential cation channel subfamily V member... 1 0
Integrin beta-1 and Integrin alpha-5 inhibitor 2-[(2,6-dimethy... 9 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00412542 CHEMBL218144 Bioactive N-(5-methoxy-2-adamantyl)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanamide
CFAMM00412548 CHEMBL375156 Bioactive AGN-PC-00AVLQ
CFAMM00412540 CHEMBL219443 Bioactive N-(5-hydroxy-7-methoxy-2-adamantyl)-2-methyl-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanamide
CFAMM00412547 CHEMBL425104 Bioactive SureCN232584
CFAMM00412553 CHEMBL219142 Bioactive SureCN232315
CFAMM00412552 CHEMBL374922 Bioactive N-(5,7-dihydroxy-2-adamantyl)-2-methyl-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]propanamide
CFAMM00412550 CHEMBL424937 Bioactive HSD Inhibitor 23

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26830 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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