CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11923
Family Name Adenosine receptor A3 ligand 3-(cyclopropylmethyl)-8-methoxy-1-[(4-methylphenyl)methyl]purino[7,8-a]pyridine-2,4-dione family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00412598 Functional Category Bioactive
Superfamily Adenosine receptor A2a and Amine oxidase [flavin-containing] B Binder Superfamily
Class Class 1027

Cousin Family NamesSeedsMembers
Adenosine receptor A2a Ligand KW-6002 Family 18 195
Dipeptidyl peptidase 4 Inhibitor Linagliptin Family 10 81
cAMP-specific 3',5'-cyclic phosphodiesterase 4D Inhibitor Arof... 3 196
Dipeptidyl peptidase 4 Inhibitor SSR-162369 Family 8 27
GP-531 family 1 33
Toll-like receptor 7 Ligand GS-9620 Family 2 4
Adenosine receptor A1 and Adenosine receptor A2a Ligand 8-phen... 12 213
Adenosine receptor A1 and Adenosine receptor A2b Ligand PSB-11... 34 26
Herpes simplex virus type 1 thymidine kinase Inhibitor 9-(4-hy... 2 13
Adenosine receptor A3 Ligand 1-benzyl-1h-1,3,4b,9-tetraaza-flu... 19 165
Adenosine receptor A2a Ligand (e,e)-8-(4-phenylbutadien-1-yl)c... 11 43
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 6 14
cGMP-specific 3',5'-cyclic phosphodiesterase Inhibitor SCH-577... 9 29
Adenosine receptor A2a and Adenosine receptor A1 ligand SureCN... 2 1
Dipeptidyl peptidase 4 inhibitor Xanthine Analogue 4 family 1 4
Dipeptidyl peptidase 4 inhibitor AGN-PC-046QKE family 3 5
Vascular endothelial growth factor receptor 2 ligand AC1LLCDM ... 1 2
Prelamin-A/C inhibitor CHEMBL1503535 family 1 0
Cellular tumor antigen p53 and Thyrotropin receptor ligand CHE... 1 5
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 21 32
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 10 14
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 5 4
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL2... 1 0
Prothrombin inhibitor 2-[4-methyl-5-[[[2-[6-methyl-2-oxo-3-(2-... 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 1 2
Adenosine receptor A1 ligand 3-(4-Aminophenethyl)-8-(3-noradam... 1 0
cAMP-specific 3',5'-cyclic phosphodiesterase 4D and cAMP-speci... 2 0


External ID

Functional Category

Molecule Name

CFAMM00412598 CHEMBL2181964 Bioactive 3-(cyclopropylmethyl)-8-methoxy-1-[(4-methylphenyl)methyl]purino[7,8-a]pyridine-2,4-dione

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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