CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11927
Family Name Mitogen-activated protein kinase 14 inhibitor N-[2-fluoro-5-[(11-oxo-5,6-dihydrodibenzo[2,1-b:3',1'-f][7]annulen-3-yl)amino]phenyl]furan-3-carboxamide family
No. of Seeds 4 No. of Other Members 5
Family Centroid CFAMM00412611 Functional Category Bioactive
Superfamily Mu-type opioid receptor and Mitogen-activated protein kinase 14 Binder Superfamily
Class Class 2495

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor and Vasopressin V2 receptor Ligand JT... 14 4
Histone deacetylase 2 Inhibitor N-(4-amino-3'-methoxybiphenyl-... 3 49
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Metabotropic glutamate receptor 5 Ligand N-(3-(3-cyanobenzamid... 2 13
Vasopressin V2 receptor and Vasopressin V1a receptor ligand AG... 1 7
Prostaglandin D2 receptor and Prostacyclin receptor ligand 2-[... 15 5
Mu-type opioid receptor ligand AGN-PC-075GG7 family 4 2
Sphingosine 1-phosphate receptor 1 ligand 2-methoxy-N-[(4-phen... 2 23
Mitogen-activated protein kinase 14 inhibitor Skepinone-L family 11 31
Mitogen-activated protein kinase 14 inhibitor N-[2,4-difluoro-... 4 1
Mitogen-activated protein kinase 14 inhibitor N-[2-fluoro-5-[(... 1 11
Mitogen-activated protein kinase 14 inhibitor N-[5-[[9-[[(4S)-... 2 0
Vasopressin V1a receptor and Vasopressin V2 receptor ligand AG... 4 4
Mitogen-activated protein kinase 14 inhibitor SureCN4822166 fa... 1 4
Mitogen-activated protein kinase 14 and Heat shock protein bet... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00412610 CHEMBL2182071 Bioactive N-[3-[(11-oxo-5,6-dihydrodibenzo[2,1-b:3',1'-f][7]annulen-3-yl)amino]phenyl]furan-3-carboxamide
CFAMM00412617 CHEMBL2316489 Bioactive N-[2-fluoro-5-[[9-(2-morpholin-4-ylethoxy)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulen-3-yl]amino]phenyl]furan-3-carboxamide
CFAMM00412622 CHEMBL2316494 Bioactive N-[2-fluoro-4-methyl-5-[[9-(2-morpholin-4-ylethoxy)-11-oxo-5,6-dihydrodibenzo[3,1-[7]annulen-3-yl]amino]phenyl]furan-3-carboxamide
CFAMM00412611 CHEMBL2182072 Bioactive N-[2-fluoro-5-[(11-oxo-5,6-dihydrodibenzo[2,1-b:3',1'-f][7]annulen-3-yl)amino]phenyl]furan-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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