CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11933
Family Name Rho-associated protein kinase 1 inhibitor SureCN4716133 family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00412648 Functional Category Bioactive
Superfamily Reverse transcriptase Inhibitor UK-129485 Superfamily
Class Class 1696

Cousin Family NamesSeedsMembers
Histamine H1 receptor Ligand Astemizole Family 7 240
AP26113 family 16 90
RAC-gamma serine/threonine-protein kinase Inhibitor GSK690693 ... 16 27
Cytochrome P450 2D6 and Cytochrome P450 3A4 Inhibitor 2-[3-(4-... 7 128
Platelet-derived growth factor receptor alpha and Platelet-der... 3 18
Reverse transcriptase Inhibitor UK-129485 Family 23 221
Cyclin-dependent kinase 2 and Cyclin-dependent kinase 1 inhibi... 2 22
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 6 35
Ribosomal protein S6 kinase beta-1 and Glycogen synthase kinas... 1 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 11
RAC-alpha serine/threonine-protein kinase and RAC-beta serine/... 9 0
Vascular endothelial growth factor receptor 2 and Fibroblast g... 3 11
Vascular endothelial growth factor receptor 2 and Fibroblast g... 10 3
Vascular endothelial growth factor receptor 2 ligand AGN-PC-09... 5 11
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 10
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 14
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 13
D(4) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 6
Insulin-like growth factor 1 receptor ligand 3qqu family 2 12
Insulin receptor and Insulin-like growth factor 1 receptor lig... 17 7
Dual specificity protein kinase TTK inhibitor 6-N-cyclohexyl-2... 3 1
Cathepsin K and Cathepsin L1 inhibitor CHEBI:43424 family 2 0
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 16 3
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 2 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 6 0
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 8 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 10 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 0
Tyrosine-protein kinase BTK and Tyrosine-protein kinase Lyn in... 5 7
Interleukin-1 receptor-associated kinase 4 and Interleukin-1 r... 4 0
Epidermal growth factor receptor ligand N-[3-[7-[2-methoxy-4-(... 9 3
Dual specificity protein kinase TTK inhibitor 6-N-cyclohexyl-2... 12 2
Dual specificity protein kinase TTK inhibitor 2-[1-[4-[[6-(cyc... 8 0
Rho-associated protein kinase 1 inhibitor SureCN4007647 family 8 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 2
Tyrosine-protein kinase Lck and Proto-oncogene tyrosine-protei... 4 3
Tyrosine-protein kinase SYK and Tyrosine-protein kinase ZAP-70... 3 8
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00412651 CHEMBL218868 Bioactive N-[3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-6-yl]oxyphenyl]acetamide
CFAMM00412648 CHEMBL218257 Bioactive SureCN4716133

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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