CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11934
Family Name B1 bradykinin receptor ligand methyl 2-fluoro-6-[3-fluoro-4-[(1R)-1-[[1-(3,3,3-trifluoropropanoylamino)cyclopropanecarbonyl]amino]ethyl]phenyl]benzoate family
No. of Seeds 18 No. of Other Members 17
Family Centroid CFAMM00412687 Functional Category Bioactive
Superfamily Cathepsin S and B1 bradykinin receptor Binder Superfamily
Class Class 3206

Cousin Family NamesSeedsMembers
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Cathepsin S inhibitor ethyl 2-[[3-[[(2S)-3-cyclohexyl-2-[(4-me... 2 9
Cathepsin B and Cathepsin L1 inhibitor 3-[[(2R)-2-cyano-2-[[(2... 3 4
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 3
Baculoviral IAP repeat-containing protein 2 and E3 ubiquitin-p... 1 4
Neutrophil elastase inhibitor SureCN7273831 family 2 2
B1 bradykinin receptor ligand methyl 2-fluoro-6-[3-fluoro-4-[[... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00412656 CHEMBL373803 Bioactive methyl 2-fluoro-6-[3-fluoro-4-[(1R)-1-[[1-(2,2,3,3,3-pentafluoropropanoylamino)cyclopropanecarbonyl]amino]ethyl]phenyl]benzoate
CFAMM00412669 CHEMBL392903 Bioactive ethyl 2,4-dichloro-6-[3-fluoro-4-[(1R)-1-[[1-[(2,2,2-trifluoroacetyl)amino]cyclopropanecarbonyl]amino]ethyl]phenyl]benzoate
CFAMM00412662 CHEMBL221288 Bioactive methyl 2-[4-[(1R)-1-[(1-acetamidocyclopropanecarbonyl)amino]ethyl]-3-fluorophenyl]-6-fluorobenzoate
CFAMM00412675 CHEMBL218267 Bioactive methyl 2-[4-[[[1-[(2-chloro-2,2-difluoroacetyl)amino]cyclopropanecarbonyl]amino]methyl]-3-fluorophenyl]-6-fluorobenzoate
CFAMM00412687 CHEMBL373530 Bioactive methyl 2-fluoro-6-[3-fluoro-4-[(1R)-1-[[1-(3,3,3-trifluoropropanoylamino)cyclopropanecarbonyl]amino]ethyl]phenyl]benzoate
CFAMM00412667 CHEMBL232943 Bioactive MK-0686
CFAMM00412680 CHEMBL219309 Bioactive methyl 2-fluoro-6-[3-fluoro-4-[[[1-(2,2,3,3,3-pentafluoropropanoylamino)cyclopropanecarbonyl]amino]methyl]phenyl]benzoate
CFAMM00412673 CHEMBL220371 Bioactive methyl 2-[4-[(1R)-1-[[1-[(2-chloro-2,2-difluoroacetyl)amino]cyclopropanecarbonyl]amino]ethyl]-3-fluorophenyl]-6-fluorobenzoate
CFAMM00412653 CHEMBL374580 Bioactive methyl 2-fluoro-6-[3-fluoro-4-[(1R)-1-[[1-[(2,2,2-trifluoroacetyl)amino]cyclopropanecarbonyl]amino]ethyl]phenyl]benzoate
CFAMM00412679 CHEMBL424919 Bioactive methyl 2-[4-[[[1-[(2,2-dichloroacetyl)amino]cyclopropanecarbonyl]amino]methyl]-3-fluorophenyl]-6-fluorobenzoate
CFAMM00412685 CHEMBL391491 Bioactive methyl 4-chloro-2-[3-fluoro-4-[(1R)-1-[[1-[(2,2,2-trifluoroacetyl)amino]cyclopropanecarbonyl]amino]ethyl]phenyl]benzoate
CFAMM00412672 CHEMBL231734 Bioactive methyl 4-chloro-2-fluoro-6-[3-fluoro-4-[(1R)-1-[[1-[(2,2,2-trifluoroacetyl)amino]cyclopropanecarbonyl]amino]ethyl]phenyl]benzoate
CFAMM00412678 CHEMBL218553 Bioactive ethyl 2-chloro-6-[3-fluoro-4-[(1R)-1-[[1-[(2,2,2-trifluoroacetyl)amino]cyclopropanecarbonyl]amino]ethyl]phenyl]benzoate
CFAMM00412671 CHEMBL219083 Bioactive SureCN1713145
CFAMM00412677 CHEMBL218552 Bioactive methyl 2-[4-[[[1-[(2-chloro-2-fluoroacetyl)amino]cyclopropanecarbonyl]amino]methyl]-3-fluorophenyl]-6-fluorobenzoate
CFAMM00412657 CHEMBL233968 Bioactive methyl 2,4-dichloro-6-[3-fluoro-4-[(1R)-1-[[1-[(2,2,2-trifluoroacetyl)amino]cyclopropanecarbonyl]amino]ethyl]phenyl]benzoate
CFAMM00412670 CHEMBL414962 Bioactive methyl 2-[4-[(1R)-1-[[1-[(2,2-difluoroacetyl)amino]cyclopropanecarbonyl]amino]ethyl]-3-fluorophenyl]-6-fluorobenzoate
CFAMM00412676 CHEMBL413775 Bioactive methyl 2-fluoro-6-[3-fluoro-4-[[[1-[(2,2,2-trifluoroacetyl)amino]cyclopropanecarbonyl]amino]methyl]phenyl]benzoate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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