CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11939
Family Name 5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine receptor 2C ligand 7-(4-fluorophenyl)-N-(3-methylpentan-3-yl)-2,3-dihydro-1H-1,4-diazepin-5-amine family
No. of Seeds 9 No. of Other Members 12
Family Centroid CFAMM00412733 Functional Category Bioactive
Superfamily Alpha adrenergic receptor Ligand Tolazoline Superfamily
Class Class 45

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1D and Alpha-1A adrenergic recept... 3 22
Sodium-dependent dopamine transporter and Sodium-dependent nor... 28 71
Nitric oxide synthase, brain Inhibitor 1-(benzhydrylamino)etha... 1 4
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 6
Glutamate receptor ionotropic, NMDA 2B ligand N'-[(3,5-dimethy... 1 1
Retinal dehydrogenase 1 and Nuclear receptor ROR-gamma ligand ... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00412740 CHEMBL436513 Bioactive N-(2-cyclobutylpropan-2-yl)-7-(2,4-difluorophenyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
CFAMM00412733 CHEMBL219265 Bioactive 7-(4-fluorophenyl)-N-(3-methylpentan-3-yl)-2,3-dihydro-1H-1,4-diazepin-5-amine
CFAMM00412739 CHEMBL373966 Bioactive 7-(2,4-difluorophenyl)-N-(1-ethylcyclopentyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
CFAMM00412725 CHEMBL219215 Bioactive 7-(4-fluorophenyl)-N-(1-methylcyclohexyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
CFAMM00412738 CHEMBL221250 Bioactive N-(1-ethylcyclopentyl)-7-(4-fluorophenyl)-2,3-dihydro-1H-1,4-diazepin-5-amine
CFAMM00412730 CHEMBL218589 Bioactive 7-(4-methylphenyl)-N-(2-methyl-1-phenylpropan-2-yl)-2,3-dihydro-1H-1,4-diazepin-5-amine
CFAMM00412736 CHEMBL386612 Bioactive 7-(2-fluorophenyl)-N-(2-methyl-1-phenylpropan-2-yl)-2,3-dihydro-1H-1,4-diazepin-5-amine
CFAMM00412729 CHEMBL218587 Bioactive 7-(2,4-difluorophenyl)-N-(3-ethylpentan-3-yl)-2,3-dihydro-1H-1,4-diazepin-5-amine
CFAMM00412735 CHEMBL386613 Bioactive N-(1-ethylcyclopentyl)-7-(2-fluorophenyl)-2,3-dihydro-1H-1,4-diazepin-5-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

69915 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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