CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1195
Family Name Neutrophil elastase inhibitor SureCN7276506 family
No. of Seeds 2 No. of Other Members 7
Family Centroid CFAMM00320459 Functional Category Bioactive with Natural Product
Superfamily Neutrophil elastase and Chymotrypsin-C Binder Superfamily
Class Class 3304

Cousin Family NamesSeedsMembers
Elagolix family 43 98
Flovagatran family 12 546
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Cathepsin F Inhibitor Benzoyl-tyrosine-alanine-methyl Ketone F... 34 55
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Potassium voltage-gated channel subfamily KQT member 1 Ligand ... 5 17
Neutrophil elastase inhibitor (2S)-N-[(3S)-6-benzamido-5,5-dif... 6 10
Neutrophil elastase inhibitor benzyl N-[2-(4-aminophenyl)-6-ox... 4 23
Neutrophil elastase inhibitor SureCN7276766 family 3 6
Neutrophil elastase and Chymotrypsin-C inhibitor benzyl N-[6-(... 3 6
Neutrophil elastase inhibitor benzyl 2-[2,4,8-trioxo-7-[2-oxo-... 2 2
Neutrophil elastase inhibitor benzyl N-[(2S)-1-[(2S)-2-[[(3S)-... 4 0
Vasopressin V1b receptor ligand AGN-PC-00HJ2S family 4 6
C-C chemokine receptor type 2 and Potassium voltage-gated chan... 2 3
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Neutrophil elastase inhibitor SureCN7273831 family 2 2
Protease inhibitor AC1O54RX family 2 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00320459 CHEMBL113171 Bioactive SureCN7276506
CFAMM00320458 CHEMBL11335 Bioactive benzyl N-[2-(4-methoxyphenyl)-6-oxo-1-[2-oxo-2-[(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)amino]ethyl]pyrimidin-5-yl]carbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

24862 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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