CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1196
Family Name Neutrophil elastase inhibitor SureCN7284457 family
No. of Seeds 4 No. of Other Members 6
Family Centroid CFAMM00320464 Functional Category Bioactive
Superfamily Neutrophil elastase and Calcitonin gene-related peptide type 1 receptor Binder Superfamily
Class Class 3307

Cousin Family NamesSeedsMembers
HIV-1 protease Inhibitor Atazanavir Family 16 58
Histone deacetylase 1 Inhibitor MS-275 Family 4 41
Substance-K receptor and Substance-P receptor Ligand L-732138 ... 8 147
Alpha-1A adrenergic receptor Ligand L-771688 Family 8 14
Pol polyprotein inhibitor pyridin-2-ylmethyl N-[(2R)-1-[[(2S,3... 15 8
Neutrophil elastase inhibitor benzyl N-[2-(4-aminophenyl)-6-ox... 4 23
Plasmepsin-1 and Plasmepsin-2 inhibitor Statine-like inhibitor... 13 5
Neutrophil elastase inhibitor 2-[2-oxo-6-phenyl-3-(2-pyridin-2... 1 2
Pol polyprotein inhibitor Carbamic acid, ((2-hydroxy-1,4-bis(p... 21 1
Cathepsin L1 and Cathepsin K inhibitor benzyl N-[(2S)-1-oxo-3-... 1 1
Calpain-2 catalytic subunit and Calpain-1 catalytic subunit in... 8 8
Calpain-1 catalytic subunit and Cathepsin B inhibitor AGN-PC-0... 5 2
Cruzipain and Cathepsin L1 inhibitor pyridin-3-ylmethyl N-[(2S... 7 4
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-3-[5-methy... 4 5
Metabotropic glutamate receptor 5 ligand AGN-PC-075X3Y family 2 6
Cathepsin K and Cathepsin S inhibitor dipeptidyl nitrile, 16b ... 2 0
Pol polyprotein inhibitor AC1LAHRX family 4 0
Probable G-protein coupled receptor 142 ligand (2S)-N-(2-oxo-5... 2 1
Neutrophil elastase inhibitor N-[(2S)-3-methyl-1-oxo-1-[(2S)-2... 4 4
Integrin beta-3 and Integrin alpha-IIb inhibitor SureCN7013744... 2 3
Prothrombin inhibitor AGN-PC-073GVF family 12 1
Neutrophil elastase inhibitor AGN-PC-0745BY family 1 0
Melanin-concentrating hormone receptor 1 ligand SureCN4917950 ... 3 5
Melanin-concentrating hormone receptor 1 and Potassium voltage... 2 4
Calcitonin gene-related peptide type 1 receptor ligand SureCN1... 1 0
Protein-glutamine gamma-glutamyltransferase 2 and Coagulation ... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00320464 CHEMBL275043 Bioactive SureCN7284457
CFAMM00320475 CHEMBL113905 Bioactive pyridin-2-ylmethyl N-[2-oxo-1-[2-oxo-2-[(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)amino]ethyl]-6-phenylpyridin-3-yl]carbamate
CFAMM00320466 CHEMBL113187 Bioactive (2,6-dimethylpyridin-4-yl)methyl N-[2-oxo-1-[2-oxo-2-[(1,1,1-trifluoro-4-methyl-2-oxopentan-3-yl)amino]ethyl]-6-phenylpyridin-3-yl]carbamate
CFAMM00320472 CHEMBL418822 Bioactive AGN-PC-00FJ6T

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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