CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11968
Family Name Pol polyprotein inhibitor SureCN4637317 family
No. of Seeds 19 No. of Other Members 6
Family Centroid CFAMM00412951 Functional Category Bioactive
Superfamily Pol polyprotein and Prelamin-A/C Binder Superfamily
Class Class 3749

Cousin Family NamesSeedsMembers
HIV protease Inhibitor Amprenavir Family 7 15
Pol polyprotein inhibitor AC1LAPRV family 13 7
Pol polyprotein inhibitor Lysine Sulfonamide 14a family 12 3
Pol polyprotein inhibitor AC1LAGJO family 6 1
Neutrophil collagenase and Stromelysin-1 inhibitor 7-[[(2S)-2-... 10 9
Neutrophil collagenase and Stromelysin-1 inhibitor tert-butyl ... 2 0
Pol polyprotein inhibitor SureCN4782454 family 5 3
Pol polyprotein inhibitor SureCN4672756 family 5 0
Pol polyprotein inhibitor AC1L9X2E family 1 2
Collagenase 3 and Matrix metalloproteinase-9 inhibitor 1-acety... 6 7


External ID

Functional Category

Molecule Name

CFAMM00412956 CHEMBL415592 Bioactive (5S)-N-[(2S,3R)-4-[cyclopropylmethyl-(4-methoxyphenyl)sulfonylamino]-3-hydroxy-1-phenylbutan-2-yl]-3-(3,4-difluorophenyl)-2-oxo-1,3-oxazolidine-5-carboxamide
CFAMM00412949 CHEMBL220454 Bioactive SureCN8250054
CFAMM00412955 CHEMBL415591 Bioactive (5S)-3-(4-acetylphenyl)-N-[(2S,3R)-3-hydroxy-4-[(3-methoxyphenyl)sulfonyl-(2-methylpropyl)amino]-1-phenylbutan-2-yl]-2-oxo-1,3-oxazolidine-5-carboxamide
CFAMM00412948 CHEMBL384438 Bioactive 2i0d
CFAMM00412954 CHEMBL414056 Bioactive SureCN4637385
CFAMM00412960 CHEMBL220079 Bioactive SureCN4638047
CFAMM00412947 CHEMBL384439 Bioactive SureCN4637645
CFAMM00412953 CHEMBL414057 Bioactive SureCN12513208
CFAMM00412966 CHEMBL385345 Bioactive SureCN4637390
CFAMM00412946 CHEMBL384436 Bioactive SureCN4638050
CFAMM00412959 CHEMBL414279 Bioactive (5S)-N-[(2S,3R)-3-hydroxy-4-[2-methylpropyl-[4-(trifluoromethoxy)phenyl]sulfonylamino]-1-phenylbutan-2-yl]-2-oxo-3-[3-(trifluoromethyl)phenyl]-1,3-oxazolidine-5-carboxamide
CFAMM00412952 CHEMBL266950 Bioactive SureCN4638252
CFAMM00412965 CHEMBL382400 Bioactive 3gi6
CFAMM00412945 CHEMBL384437 Bioactive SureCN8246093
CFAMM00412958 CHEMBL413489 Bioactive (5S)-N-[(2S,3R)-4-[cyclopropylmethyl-(4-methoxyphenyl)sulfonylamino]-3-hydroxy-1-phenylbutan-2-yl]-3-(3-fluorophenyl)-2-oxo-1,3-oxazolidine-5-carboxamide
CFAMM00412951 CHEMBL219696 Bioactive SureCN4637317
CFAMM00412964 CHEMBL266949 Bioactive SureCN4637341
CFAMM00412957 CHEMBL219748 Bioactive 2i0a
CFAMM00412963 CHEMBL385790 Bioactive SureCN12513203

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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