CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM1197
Family Name D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-chlorophenyl)-3-[2-(4-methylpiperidin-1-yl)ethyl]imidazolidin-2-one family
No. of Seeds 6 No. of Other Members 12
Family Centroid CFAMM00310552 Functional Category Bioactive
Superfamily Dopamine receptor Ligand Domperidone Superfamily
Class Class 221

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 10 157
Dopamine receptor Ligand Domperidone Family 2 21
Sigma non-opioid intracellular receptor 1 Ligand MS-377 Family 1 21
Gamma-aminobutyric acid A receptor Ligand ELB-139 Family 1 3
Nociceptin receptor Ligand J-113397 Family 3 14
Bifunctional epoxide hydrolase 2 Inhibitor 1-(3-chloro-phenyl)... 5 50
Bifunctional epoxide hydrolase 2 Inhibitor N-(3-chloro-phenyl)... 2 43
Androgen receptor Ligand YM-175735 Family 30 129
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 3 34
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 6 45
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 4 24
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 4 18
D(2) dopamine receptor and D(3) dopamine receptor ligand AGN-P... 5 5
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 3 1
Melanin-concentrating hormone receptor 1 ligand 3-(3-chloro-4-... 8 24
Survival motor neuron protein and Retinal dehydrogenase 1 inhi... 1 1
Substance-P receptor ligand (2S,4S)-2-N-[3-(diethylamino)propy... 2 7
C-C chemokine receptor type 2 and C-C chemokine receptor type ... 2 8
D(3) dopamine receptor and D(2) dopamine receptor ligand 3-[4-... 4 23
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 11 3
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 5 2
D(3) dopamine receptor and D(2) dopamine receptor ligand RGH-1... 8 0
Melanin-concentrating hormone receptor 1 ligand SureCN14265866... 11 2
Substance-P receptor and Mu-type opioid receptor ligand ethyl ... 1 0
Histamine H3 receptor and Histamine receptor H3 ligand N-[4-[3... 5 1
Histamine H3 receptor and Histamine receptor H3 ligand 1-(3,5-... 4 0
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 3
Kappa-type opioid receptor ligand AGN-PC-077Q4Y family 5 9
Kappa-type opioid receptor and Urotensin-2 receptor ligand 2-(... 5 1
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 1
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 3 1
Alpha-1D adrenergic receptor and Alpha-1B adrenergic receptor ... 2 0
Neuropeptide Y receptor type 5 ligand 3-[1-(3,5-dichlorophenyl... 1 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-[2-... 3 1
D(3) dopamine receptor and D(2) dopamine receptor ligand AGN-P... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 4 3
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-[2-... 2 2
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 1 0
Potassium voltage-gated channel subfamily H member 2 and D(3) ... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand 1-(3-... 2 1
Bloom syndrome protein and Prelamin-A/C inhibitor DCEBIO family 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00320480 CHEMBL114100 Bioactive SureCN7273361
CFAMM00320479 CHEMBL113213 Bioactive SureCN7275888

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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