CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11972
Family Name Muscarinic acetylcholine receptor M5 and Muscarinic acetylcholine receptor M1 ligand (2R,5S)-2-cyclohexyl-5-[(2S)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-phenyl-1,3-oxathiolane 3-oxide;iodide family
No. of Seeds 6 No. of Other Members 10
Family Centroid CFAMM00412998 Functional Category Bioactive
Superfamily Nicotinic acetylcholine receptor Ligand Benztropine Mesylate Superfamily
Class Class 682

Cousin Family NamesSeedsMembers
Sigma non-opioid intracellular receptor 1 ligand SureCN7425449... 2 0


External ID

Functional Category

Molecule Name

CFAMM00413008 CHEMBL219786 Bioactive (2S)-2-[(2R,5S)-2-cyclohexyl-2-phenyl-1,3-oxathiolan-5-yl]-1,1-dimethylpyrrolidin-1-ium;iodide
CFAMM00412998 CHEMBL539120 Bioactive (2R,5S)-2-cyclohexyl-5-[(2S)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-phenyl-1,3-oxathiolane 3-oxide;iodide
CFAMM00413004 CHEMBL376057 Bioactive (2S)-2-[(2S,5S)-2-cyclohexyl-2-phenyl-1,3-oxathiolan-5-yl]-1,1-dimethylpyrrolidin-1-ium;iodide
CFAMM00413003 CHEMBL539121 Bioactive (2R,5R)-2-cyclohexyl-5-[(2R)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-phenyl-1,3-oxathiolane 3-oxide;iodide
CFAMM00413012 CHEMBL493980 Bioactive (2R,5S)-2-cyclohexyl-5-[(2S)-1-methylpyrrolidin-2-yl]-2-phenyl-1,3-oxathiolane 3-oxide
CFAMM00413011 CHEMBL493979 Bioactive (2S,5R)-2-cyclohexyl-5-[(2R)-1-methylpyrrolidin-2-yl]-2-phenyl-1,3-oxathiolane 3-oxide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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