CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11981
Family Name Mitogen-activated protein kinase 1 inhibitor Pyrrole Carboxamide Analog 6o family
No. of Seeds 3 No. of Other Members 12
Family Centroid CFAMM00413140 Functional Category Bioactive
Superfamily Cannabinoid receptor 1 and Cannabinoid receptor 2 Binder Superfamily 7
Class Class 4628

Cousin Family NamesSeedsMembers
Dihydroorotate dehydrogenase (quinone), mitochondrial inhibito... 2 21
Cyclin-A2 and Cyclin-dependent kinase 2 inhibitor dihydro-benz... 3 5
Dipeptidyl peptidase 9 and Dipeptidyl peptidase 8 inhibitor 3-... 3 6
Rho-associated protein kinase 2 and Rho-associated protein kin... 2 6
Ribosomal protein S6 kinase alpha-3 inhibitor 1-oxo-N-[1-(pyri... 5 11
Coagulation factor X inhibitor SureCN8169809 family 12 18
Serine/threonine-protein kinase PLK4 inhibitor (3E)-3-[[3-[(E)... 5 2
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 4 1
Acetyl-CoA carboxylase 2 and Acetyl-CoA carboxylase 1 inhibito... 3 0
Mitogen-activated protein kinase 1 and Aurora kinase A inhibit... 16 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00413139 CHEMBL220897 Bioactive Pyrrole Carboxamide Analog 6n
CFAMM00413144 CHEMBL387385 Bioactive (S)-N-(1-(3-Chloro-4-Fluorophenyl)-2-Hydroxyethyl)-4-(4-(3-Chlorophenyl)-1h-Pyrazol-3-Yl)-1h-Pyrrole-2-Carboxamide
CFAMM00413140 CHEMBL220054 Bioactive Pyrrole Carboxamide Analog 6o

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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