CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM11990
Family Name Neuronal acetylcholine receptor subunit alpha-4 and Neuronal acetylcholine receptor subunit beta-2 ligand SureCN653978 family
No. of Seeds 7 No. of Other Members 0
Family Centroid CFAMM00162177 Functional Category Bioactive
Superfamily Neuronal acetylcholine receptor subunit beta-2 and Neuronal acetylcholine receptor subunit alpha-4 Binder Superfamily 2
Class Class 1668

Cousin Family NamesSeedsMembers
Nicotinic acetylcholine receptor Ligand Nicotine Family 14 686
Histamine H1 receptor Ligand Triprolidine Family 19 316
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor Ethion... 5 68
G protein-activated inward rectifier potassium channel 4 Ligan... 3 48
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 23 63
Nicotinic acetylcholine receptor Ligand Epibatidine Family 36 19
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 13 26
Acetylcholinesterase and Cholinesterase Inhibitor 1,9-bis(pyri... 8 38
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 4 6
Metabotropic glutamate receptor 5 Ligand 5-((6-methylpyridin-2... 14 22
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 4 5
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 0
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 1 4
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 2 2
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 5 2
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 3
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 3 1
Neuronal acetylcholine receptor subunit alpha-4 and Neuronal a... 10 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00413179 CHEMBL468064 Bioactive 5-[(1S,6R)-4,7-diazabicyclo[4.2.0]octan-7-yl]pyridine-3-carbonitrile
CFAMM00413178 CHEMBL448697 Bioactive 2-bromo-5-[(1R,6S)-4,7-diazabicyclo[4.2.0]octan-7-yl]pyridine-3-carbonitrile
CFAMM00413177 CHEMBL374692 Bioactive 2-bromo-5-[(1S,6R)-4,7-diazabicyclo[4.2.0]octan-4-yl]pyridine-3-carbonitrile
CFAMM00413176 CHEMBL220295 Bioactive 2-bromo-5-[(1S,6R)-4,7-diazabicyclo[4.2.0]octan-7-yl]pyridine-3-carbonitrile
CFAMM00413180 CHEMBL426879 Bioactive SureCN651868

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27701 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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